High-Resolution Mass Spectrometry Services
High-resolution mass spectrometry services provide powerful analytical capabilities for precise molecular mass determination and structural characterization. Compared to low-resolution mass spectrometry, high-resolution mass spectrometry services offer superior mass accuracy, achieving sub-ppm precision, and provide detailed fragmentation patterns, significantly enhancing analytical reliability. The extensive applications of this technology enable researchers to conduct in-depth investigations of biological systems, optimize drug development, ensure food safety, and monitor environmental contaminants.
In proteomics, high-resolution mass spectrometry services are widely employed for protein identification, post-translational modification (PTM) analysis, and quantitative proteomics. In pharmaceutical and metabolomics research, these services facilitate small molecule structural elucidation, metabolite profiling, impurity analysis, and pharmacokinetics studies. This technology enables the detection of drugs and their metabolites at trace levels, ensuring pharmaceutical safety and efficacy.
In food safety testing, high-resolution mass spectrometry services are utilized to detect pesticide residues, veterinary drug residues, illegal additives, and heavy metal contaminants in food products. Given the complexity of food matrices, conventional detection methods often struggle to accurately identify and quantify target contaminants. High-resolution mass spectrometry, with its ability to resolve structurally similar analytes, significantly improves detection sensitivity and specificity.
In environmental monitoring, high-resolution mass spectrometry services are instrumental in detecting persistent organic pollutants (POPs), industrial waste, and microplastic contaminants in air, water, and soil.
High-resolution mass spectrometry services provide distinct advantages over low-resolution mass spectrometry. Their ultra-high resolution enables the differentiation of compounds with minimal mass differences, ensuring accurate identification. Their exceptional sensitivity allows for trace-level analysis, making them ideal for detecting low-abundance compounds. Furthermore, high-resolution mass spectrometry services deliver highly precise mass measurements, facilitating accurate molecular formula determination. With broad applicability across biology, chemistry, medicine, food science, and environmental science, these services meet the analytical demands of diverse research fields.
Key high-resolution mass spectrometry technologies include Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), Orbitrap mass spectrometry (Orbitrap MS), and time-of-flight mass spectrometry (TOF-MS). FT-ICR MS leverages strong magnetic fields to confine charged ions in circular trajectories, calculating ion masses via Fourier transform, achieving ultra-high resolution for the precise analysis of complex mixtures. Orbitrap MS integrates electrostatic trapping with Fourier transform technology, offering high resolution and sensitivity, making it a leading method in proteomics and metabolomics. TOF-MS determines ion mass by measuring ion flight time in a vacuum, making it highly effective for rapid screening of unknown compounds. When coupled with liquid chromatography (LC) or gas chromatography (GC), TOF-MS enables high-throughput analysis of complex samples. These cutting-edge technologies ensure that high-resolution mass spectrometry services deliver high-quality data and enhance analytical efficiency across multiple disciplines.
MtoZ Biolabs provides high-precision high-resolution mass spectrometry services, supporting applications such as protein identification, PTM analysis, metabolomics, pharmaceutical analysis, and food safety testing. Leveraging state-of-the-art mass spectrometry technologies, our expert team ensures accurate, high-throughput molecular identification and quantification with exceptional data reliability and reproducibility.
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider.
Related Services
How to order?
