IMP Analysis Service
- Accurate quantification of IMP using high-resolution mass spectrometry.
- Comprehensive metabolic coverage with our advanced analytical platforms.
- Detailed data analysis with our expert bioinformatics team.
- Expert team with extensive experience in metabolomics analysis.
- Advanced technology platform ensuring high sensitivity and accuracy.
- Comprehensive data report providing in-depth analysis.
- Excellent customer service to assist you throughout the project.
- Disease biomarker discovery and validation.
- Drug metabolism and pharmacokinetics.
- Personalized medicine and nutrition.
- Samples should be kept frozen and shipped on dry ice.
- We recommend providing at least 3 samples of similar conditions for each type of sample.
- Other sample types, please contact us for more details.
Inosine monophosphate (IMP) is a nucleotide that plays a central role in purine metabolism and serves as a precursor for the synthesis of both adenosine monophosphate (AMP) and guanosine monophosphate (GMP). Structurally, IMP consists of an inosine molecule attached to a phosphate group. It is primarily formed through the deamination of adenosine monophosphate (AMP) or via the de novo purine synthesis pathway. As an intermediate in these pathways, IMP is crucial for the production of the purine nucleotides required for DNA and RNA synthesis, energy transfer, and signal transduction.
The study of IMP and its metabolic pathways is critical for understanding various physiological processes and the regulation of cellular energy. IMP levels are tightly regulated within the cell, as they directly influence the balance of other purine nucleotides. Alterations in IMP metabolism can lead to significant cellular dysfunctions, contributing to the development of diseases such as gout, where excess purine breakdown leads to elevated uric acid levels. Additionally, IMP metabolism is of interest in the context of cardiovascular diseases, where it plays a role in energy production during ischemic conditions.
Research into IMP also extends to its role in flavor enhancement, particularly in the food industry, where it is recognized as a key umami component in meats and broths. Understanding the metabolism and regulation of IMP is therefore not only important in a medical context but also has applications in food science.
Figure 1. The Structure of IMP
MtoZ Biolabs is excited to offer a specialized IMP Analysis Service, utilizing advanced mass spectrometry techniques to provide accurate and detailed quantification of IMP. Our service is designed to support researchers in exploring the complexities of purine metabolism and its implications in health, disease, and beyond.
At MtoZ Biolabs, we are equipped to handle complex analytical challenges. We provide:
Analysis Workflow
1. Sample Preparation: We accept various types of samples for IMP analysis, including cells, tissues, and biofluids.
2. Metabolite Extraction: Metabolites are extracted using a validated protocol, ensuring high recovery of IMP.
3. LC-MS/MS Analysis: The extracted metabolites are analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS), ensuring high sensitivity and specificity.
4. Data Analysis and Report: Our expert bioinformatics team performs data pre-processing, statistical analysis, pathway analysis, and provides the final report.
Service Advantages
Applications
Our IMP Analysis Service is applicable in various areas including:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on IMP
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to providing you with reliable, comprehensive, and high-quality services for your IMP analysis needs.
How to order?
