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    Indole-3-Glyoxylic Acid Analysis Service

      Indole-3-glyoxylic acid is an indole derivative characterized by a glyoxylic acid moiety attached to the indole ring. This unique molecular structure may influence its biological properties and interactions with various biochemical pathways. The combination of the indole ring and glyoxylic acid group can affect its physicochemical properties, such as solubility and reactivity, thereby impacting its absorption, distribution, metabolism, and excretion (ADME) profiles within the body. These structural features could potentially alter its bioavailability and biological activity.

       

      Metabolomics analysis, utilizing high-throughput techniques such as mass spectrometry and nuclear magnetic resonance, can comprehensively elucidate the metabolic pathways and mechanisms of indole-3-glyoxylic acid within the body. Compared to traditional metabolic analysis methods, metabolomics can detect a wider range of metabolites and their concentration changes, providing a more comprehensive understanding of the compound's metabolic network. Through this approach, both primary and secondary metabolic pathways of indole-3-glyoxylic acid can be identified, including biochemical reactions involving specific enzymes, which help in understanding how this compound is metabolized in different tissues and organs. Metabolomics analysis can also identify various metabolites of indole-3-glyoxylic acid and their structural characteristics, including active metabolites and potentially toxic ones. This is crucial for elucidating the pharmacological effects and toxicological properties of the compound. For example, some metabolites may exhibit greater biological activity or toxicity than the parent compound; metabolomics analysis can help discover these key metabolites and investigate their potential impacts.

       

      1831209142237908992-TheStructureofIndole-3-GlyoxylicAcid.png

      Figure 1. The Structure of Indole-3-Glyoxylic Acid

       

      MtoZ Biolabs offers an exceptional Indole-3-Glyoxylic Acid Analysis Service, utilizing our cutting-edge liquid chromatography-mass spectrometry (LC-MS) platform and team of metabolomics experts. Our service provides a thorough analysis of indole-3-glyoxylic acid, ensuring high sensitivity and accuracy.

       

      Analysis Workflow

       

      1831209219262107648-WorkflowofIndole-3-GlyoxylicAcidAnalysisService.PNG

       

      Service Advantages

      1. High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.

       

      2. Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.

       

      3. Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.

       

      4. Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.

       

      Applications

      • Qualitative analysis of the metabolites of indole-3-glyoxylic acid
      • Quantitative analysis of indole-3-glyoxylic acid content
      • Provide basis for pharmacological studies and therapeutic improvements

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. For each sample, more than 3 materials of the same condition must be selected.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C to maintain stability.

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Indole-3-Glyoxylic Acid

      4. Raw Data

      5. Custom Analysis Report

       

      By availing our indole-3-glyoxylic acid analysis service, we aim to assist your research and product development processes by delivering accurate and reliable results, thereby enabling you to accelerate your studies and innovations in the domain.

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