Isocitric Acid Analysis Service
- Disease Diagnosis: Detection of abnormal isocitric acid levels for disease diagnosis.
- Drug Development: Studying the effect of new drugs on isocitric acid levels.
- Metabolic Research: Understanding the role of isocitric acid in various metabolic pathways.
- We accept diverse biological samples, including but not limited to cells, tissues, biofluids.
- Please ensure your submitted sample surpasses 0.2 g or 0.2 mL.
- Samples should be stored in a -80℃ environment and transported on dry ice.
Isocitrate, a structural isomer of citrate, shares similar physical and chemical properties with its counterpart. It is a critical metabolic product of the tricarboxylic acid cycle (TCA), where it significantly contributes to energy generation and the provision of carbon skeletons essential for various biosynthetic processes. Deviations in isocitrate levels are associated with numerous metabolic disorders, underscoring the importance of its accurate measurement for diagnosing diseases, advancing drug development, and furthering metabolic studies. Research has also identified isocitrate as a potential therapeutic for conditions such as iron deficiency anemia and Parkinson's disease, highlighting its significant role in medical applications.
Figure 1. The Structure of Isocitric Acid
Services at MtoZ Biolabs
Our Isocitric Acid Analysis Service is based on Liquid Chromatography-Mass Spectrometry (LC-MS). LC-MS is a powerful analytical method that combines the separation capabilities of liquid chromatography with the detection properties of mass spectrometry. In this process, your sample is first separated into its individual components by liquid chromatography and then analyzed by mass spectrometry. This double analysis ensures high precision and sensitivity in detecting isocitric acid even in complex biological samples.
Analysis Workflow
Applications
Our Isocitric Acid Analysis Service can be applied in various fields, including:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Isocitric Acid Analysis
4. Mass Spectrometry Images
5. Raw Data
At MtoZ Biolabs, we are committed to offering you the highest quality of Isocitric Acid Analysis Service. If you have any questions or need further information, please don't hesitate to contact us.
How to order?
