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    Keratan Sulfate Analysis Service

      Keratan sulfate (KS) is a glycosaminoglycan characterized by its repeating disaccharide units of galactose and N-acetylglucosamine, which are often sulfated. It is primarily found in various connective tissues, including cartilage, cornea, and the nervous system. KS plays a pivotal role in modulating cellular functions and maintaining extracellular matrix structure due to its capacity to bind with proteins such as growth factors, cytokines, and adhesion molecules.

       

      In cartilage, KS contributes to the tissue’s resilience and shock-absorbing properties by interacting with collagen and providing compressive strength. In the cornea, it helps maintain transparency and light refraction properties essential for vision. Additionally, in the nervous system, KS is involved in neural development and repair processes, influencing cell adhesion and migration.

       

      Moreover, abnormalities in KS metabolism are linked to several pathologies, including osteoarthritis and certain types of macular degeneration. Therefore, understanding the role and mechanisms of keratan sulfate in biological systems is crucial for developing therapeutic interventions for these diseases.

       

      Services at MtoZ Biolabs

      At MtoZ Biolabs, we utilize our ultra-performance liquid chromatography-mass spectrometry tandem (UPLC-MS/MS) detection platform for the rapid and accurate identification and quantitative analysis of keratan sulfate. Our advanced techniques and state-of-the-art equipment enable us to provide precise and reliable results.

       

      Analysis Workflow

       

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      Service Advantages

      • High Sensitivity and Accuracy: Our advanced mass spectrometry techniques ensure highly sensitive and accurate analysis of Keratan Sulfate.
      • Skilled Experts: Our team comprises skilled experts with extensive experience in metabolomics and mass spectrometry.
      • Custom Solutions: We offer custom solutions tailored to your specific research needs.
      • Quick Turnaround: We strive to deliver results in a timely manner without compromising on quality.

       

      Sample Submission Requirements

      • Please ensure your submitted sample surpasses 0.2 g or 0.2 mL.
      • Samples should be stored in a -80℃ environment and transported on dry ice.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Keratan Sulfate Analysis

      4. Mass Spectrometry Images

      5. Raw Data

       

      To learn more about our Keratan Sulfate Analysis Service or other services we offer, contact us today. Our team is ready to assist you in your research journey. With MtoZ Biolabs, experience the best of metabolomics analysis services.

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