Kynurenic Acid Analysis Service

Kynurenic acid is a crucial metabolite in the tryptophan metabolic pathway, widely present in mammalian tissues. It plays multiple roles in the nervous system, including neuroprotection, anti-inflammatory, and antioxidant functions. As an endogenous NMDA receptor antagonist and α7 nicotinic acetylcholine receptor antagonist, kynurenic acid is important in the pathophysiology of neurodegenerative diseases, psychiatric disorders, and inflammatory diseases. Accurate analysis of kynurenic acid is essential for basic research, clinical diagnostics, and drug development.

Figure 1. Molecular Structure of Kynurenic Acid

MtoZ Biolabs offers Kynurenic Acid Analysis Service using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). This advanced method combines the separation capabilities of UPLC with the detection power of MS, ensuring high sensitivity and specificity in kynurenic acid detection.

Analysis Workflow

Service Advantages

1. High Sensitivity

Detects very low concentrations of kynurenic acid accurately.

2. High Specificity

Differentiates kynurenic acid from other compounds using mass spectrometry.

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

5. Versatility

Capable of analyzing kynurenic acid and its related metabolites.

Sample Submission Requirements

Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

Applications

• Study the role of kynurenic acid in neuroprotection and neurodegenerative diseases.
• Detect kynurenic acid levels to assist in diagnosing and monitoring neurological, psychiatric, and inflammatory diseases.
• Evaluate the impact of drugs on kynurenic acid metabolic pathways and identify potential therapeutic targets.

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Kynurenic Acid

4. Raw Data

5. Custom Analysis Report

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into kynurenic acid's extensive physiological roles through top-tier analytical techniques and expert services.