L-Asparagine Analysis Service

L-asparagine is a non-essential amino acid that plays crucial roles in various physiological processes, including protein synthesis, amino acid metabolism, and cell signaling. It is vital for tumor cell growth and proliferation, and participates in one-carbon metabolism, which is essential for DNA and RNA synthesis. Given its significant role in these processes, precise analysis of L-asparagine and its metabolites is essential for understanding its metabolic pathways and functions.

 



Figure 1. Molecular Structure of L-Asparagine

 

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of L-asparagine and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of L-asparagine in complex biological matrices.

 

Analysis Workflow

 

Service Advantages

 

Sample Submission Requirements

1. The amino acid sample must be free from contamination by other impurities and should not precipitate after standing or centrifugation.

 

2. The standard mass for solid samples is 5 g, while liquid samples require 15 mL.

 

3. Plant tissues derived from leaves, flowers, stems, roots, or fruits should be greater than 5 g.

 

Applications

Clinical Research: Monitor L-asparagine levels to study its role in cancer, metabolic diseases, and other health conditions, aiding diagnosis and treatment.

 

Nutritional Assessment: Analyze L-asparagine content in foods and supplements to evaluate nutritional value and guide dietary intake and supplementation strategies.

 

Cancer Research: Assess the role of L-asparagine in tumor cells and study its potential applications in cancer therapy.

 

Drug Development: Explore the potential applications of L-asparagine in new drug development, particularly for treating metabolic diseases and cancer.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on L-Asparagine

4. Raw Data

5. Custom Analysis Report