L-Carnosine Analysis Service
- Liquid Chromatography-Mass Spectrometry (LC-MS)
- Gas Chromatography-Mass Spectrometry (GC-MS)
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
L-Carnosine is a dipeptide consisting of β-alanine and L-histidine, commonly found in muscle and brain tissues. Renowned for its antioxidant, anti-glycation, and metal-chelating properties, L-Carnosine plays a crucial role in cellular function and delaying aging. It is also essential for regulating muscle contraction, reducing fatigue, and promoting wound healing.
Variations in L-Carnosine levels can be linked to several physiological and pathological conditions, such as neurodegenerative diseases, diabetes, and cardiovascular diseases. Accurate measurement of L-Carnosine concentrations provides valuable insights into its role in various health conditions, forming a scientific basis for diagnosing and treating related diseases.
Figure 1. Molecular Structure of L-Carnosine
MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of L-Carnosine and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of L-Carnosine in complex biological matrices.
Analysis Workflow
Experimental Instruments
Service Advantages
Sample Submission Requirements
Sample Types
Serum, plasma, urine, tissue homogenates, and other biological samples.
Sample Volume
At least 200 μL of liquid sample or 200 mg of tissue sample.
Sample Preservation
Store and transport samples at -80°C to maintain L-Carnosine stability.
Applications
Clinical Diagnosis: Measure levels in patients with neurodegenerative diseases, diabetes, and cardiovascular diseases to assist in diagnosis and prognosis.
Metabolic Research: Investigate the role and metabolic pathways of L-Carnosine in antioxidation, anti-glycation, and metal chelation.
Drug Development: Evaluate the impact of drugs on L-Carnosine metabolism to aid in developing new therapeutic agents.
Nutritional Research: Analyze the metabolic changes of L-Carnosine under different dietary conditions, providing scientific evidence for nutritional regulation and dietary supplementation.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on L-Carnosine and their Metabolites
4. Raw Data
5. Custom Analysis Report
Our L-Carnosine analysis service provides high-quality data support, advancing your scientific research and clinical studies. For any inquiries or requirements, please contact us.
How to order?
