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    L-Glutamic Acid Analysis Service

      L-Glutamic acid (L-Glu) is a crucial non-essential amino acid widely present in the human body, involved in various key physiological and metabolic processes. It serves as a precursor to the neurotransmitter glutamate, which plays a vital role as an excitatory neurotransmitter in the central nervous system. Additionally, L-Glu is important in nitrogen metabolism, amino acid synthesis, and energy metabolism. Its metabolic products, including γ-aminobutyric acid (GABA), are essential in neural regulation and anti-anxiety responses. Given its significant role in multiple biological processes, changes in L-Glu levels are closely associated with various diseases, such as neurodegenerative disorders, liver diseases, and metabolic syndrome. Therefore, accurate analysis of L-Glu content and metabolism is essential for understanding its mechanisms in the body and its potential applications in disease diagnosis and treatment.

       

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      Figure 1. Molecular Structure of L-Glutamic Acid

       

      MtoZ Biolabs offers L-Glutamic Acid Analysis Service using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of L-Glu in complex biological matrices.

       

      Analysis Workflow

       

      l-glutamic-acid-analysis-service2

       

      Service Advantages

      • Rapid Analysis Cycle and Cost-Effectiveness
      • Stable, Reliable, and Highly Sensitive Results
      • Comprehensive One-Stop Service for Extensive Testing Needs
      • User-Friendly Operation with Wide Application Scope
      • Supported by Extensive Bioanalytical Resources and Advanced Platforms

       

      Sample Submission Requirements

      Sample Types

      Biological Fluids: Serum, plasma, urine, bile, bile acids

      Animal Tissues: Cells, liver, brain, and other animal tissues, as well as feces

      Other Samples: Plants, yeast, microorganisms

       

      Sample Volume

      At least 200 μL of liquid sample or 200 mg of tissue sample.

       

      Sample Transportation

      For shipping, it is recommended to use an adequate amount of dry ice, considering that 3-4 kg of dry ice sublimates in one day. It is advisable to use larger blocks of dry ice as they sublimate more slowly. Ensure samples are sealed in a foam box and opt for the fastest possible shipping method to minimize sample degradation during transport.

       

      Applications

      Neuroscience Research: Analyze changes in L-Glu levels to study its role in neurotransmitter synthesis and neurodegenerative diseases.

       

      Liver Disease Research: Evaluate changes in L-Glu levels in liver metabolism and liver diseases, studying its potential role in liver dysfunction.

       

      Metabolic Syndrome Research: Investigate the role of L-Glu in energy metabolism and metabolic syndrome, exploring its applications in metabolic regulation.

       

      Basic Metabolism Research: Analyze the metabolic pathways of L-Glu under normal and pathological conditions to explore its biological functions in the body.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on L-Glu and Their Metabolites

      4. Raw Data

      5. Custom Analysis Report

       

      MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into L-Glu's extensive physiological roles through top-tier analytical techniques and expert services.

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