L-Pipecolic Acid Analysis Service
- Liquid Chromatography-Mass Spectrometry (LC-MS)
- Gas Chromatography-Mass Spectrometry (GC-MS)
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
L-Pipecolic acid is a non-standard amino acid widely found in various organisms. It is a key intermediate in lysine metabolism, particularly in mammals, and its metabolic pathway is closely linked to multiple physiological functions. L-Pipecolic acid plays a significant role in the nervous system, especially in neuron growth and function. Additionally, changes in L-pipecolic acid levels are associated with various metabolic and neurodegenerative diseases, such as Wilson's disease and pyridoxine-dependent epilepsy. Therefore, accurate analysis of L-pipecolic acid content and metabolism is essential for understanding its mechanisms in the body and its potential applications in disease diagnosis and research.
Figure 1. Molecular Structure of L-Pipecolic Acid
MtoZ Biolabs offers L-Pipecolic Acid Analysis Service using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of L-pipecolic acid in complex biological matrices.
Analysis Workflow
Experimental Instruments
Service Advantages
Sample Submission Requirements
Sample Types
Serum, plasma, urine, tissue homogenates, and other biological samples.
Sample Volume
At least 200 μL of liquid sample or 200 mg of tissue sample.
Sample Preservation
Store and transport samples at -80°C.
Applications
Neuroscience Research: Analyze changes in L-pipecolic acid levels to study its role in neuron growth and neurodegenerative diseases.
Metabolic Disease Research: Evaluate changes in L-pipecolic acid levels in metabolic diseases such as Wilson's disease and pyridoxine-dependent epilepsy.
Liver Disease Research: Investigate the role of L-pipecolic acid in liver metabolism and liver diseases, exploring its potential role in liver dysfunction.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on L-Pipecolic Acid
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into L-pipecolic acid's extensive physiological roles through top-tier analytical techniques and expert services.
How to order?
