L-Sarcosine Analysis Service

L-Sarcosine is a naturally occurring amino acid derivative, an N-methylated product of glycine. It plays significant roles in various biological processes, including one-carbon unit metabolism and serving as a marker for protein degradation. L-Sarcosine is metabolically active in the liver, kidneys, and prostate. Given its critical functions in physiological and pathological states, precise analysis of L-Sarcosine concentrations is essential for understanding its roles and metabolic pathways in the body.

Figure 1. Molecular Structure of Sarcosine

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of L-Sarcosine and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of L-Sarcosine in complex biological matrices.

Analysis Workflow

Experimental Instruments

• Liquid Chromatography-Mass Spectrometry (LC-MS)
• Gas Chromatography-Mass Spectrometry (GC-MS)
• Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Service Advantages

Sample Submission Requirements

Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

Sample Volume

At least 200 μL of liquid sample or 200 mg of tissue sample.

Sample Preservation

Store and transport samples at -80°C to maintain L-Sarcosine stability.

Applications

Clinical Research: Monitor L-Sarcosine levels to study its roles in liver, kidney, and prostate diseases.

Disease Monitoring: Analyze L-Sarcosine and its metabolites to monitor pathological progress related to metabolic disorders and cancers.

Nutritional Research: Evaluate the L-Sarcosine content in foods and supplements to guide nutritional intake and health management.

Drug Development: Explore the potential applications of L-Sarcosine and its metabolites in new drug development, assessing drug efficacy and safety.

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on L-Sarcosine and their Metabolites

4. Raw Data

5. Custom Analysis Report