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    L-Theanine Analysis Service

      L-Theanine is an amino acid naturally found in tea leaves, known for its unique relaxation and stress-reducing effects. L-Theanine can cross the blood-brain barrier, affecting the central nervous system by regulating neurotransmitter release, such as dopamine and serotonin, thereby improving mood and cognitive function. In plants, L-Theanine is synthesized from glutamic acid and ethylamine through the catalysis of L-Theanine synthetase. Once ingested by humans, L-Theanine can be metabolized in the liver into ethylamine, glutamic acid, and other compounds, which play important roles in neural transmission and energy metabolism. L-Theanine also has potential antioxidant properties, enhances the immune system, and improves cardiovascular health. Accurate measurement of L-Theanine concentrations is crucial for studying its physiological and pharmacological effects and provides a scientific basis for the prevention and treatment of related diseases.

       

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      Figure 1. Molecular Structure of L-Theanine

       

      MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of L-Theanine and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of L-Theanine in complex biological matrices.

       

      Analysis Workflow

       

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      Experimental Instruments

      • Liquid Chromatography-Mass Spectrometry (LC-MS)
      • Gas Chromatography-Mass Spectrometry (GC-MS)
      • Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

       

      Service Advantages

       

      l-theanine-analysis-service3

       

      Sample Submission Requirements

      Sample Types

      Serum, plasma, urine, tissue homogenates, and other biological samples.

       

      Sample Volume

      At least 200 μL of liquid sample or 200 mg of tissue sample.

       

      Sample Preservation

      Store and transport samples at -80°C to maintain L-Theanine stability.

       

      Applications

      Neuroscience Research: Study the effects of L-Theanine on neurotransmitters and brain function, exploring its role in improving mood and cognitive function.

       

      Clinical Research: Detect changes in L-Theanine levels to evaluate its effectiveness in treating depression, anxiety, and improving sleep.

       

      Nutritional Research: Analyze the metabolic changes of L-Theanine under different dietary conditions, providing scientific evidence for nutritional supplements and dietary regulation.

       

      Drug Development: Evaluate the impact of new drugs on L-Theanine metabolism to aid in developing new neuroprotective and antioxidant drugs.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on L-Theanine and Their Metabolites

      4. Raw Data

      5. Custom Analysis Report

       

      MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into L-Theanine's extensive physiological roles through top-tier analytical techniques and expert services.

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