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    Leu-Val Analysis Service

      Leu-Val is a dipeptide composed of two amino acids: leucine (Leu) and valine (Val). Both leucine and valine are branched-chain amino acids (BCAAs) that play essential roles in protein synthesis and metabolic regulation. In the Leu-Val dipeptide, leucine is linked to valine through a peptide bond formed between the carboxyl group of leucine and the amino group of valine.

       

      The content of Leu-Val can serve as a potential biomarker for specific physiological and pathological states. In clinical and sports science, detecting the levels of Leu-Val can help assess protein metabolic status, nutritional status, muscle injury recovery, and insulin resistance. Changes in Leu-Val concentrations may be associated with certain disease conditions, such as muscle atrophy, chronic diseases, and liver diseases, making it useful for pathological diagnosis and monitoring treatment efficacy. Leu-Val can be further metabolized in the body into leucine and valine, both of which are involved in several key metabolic pathways, such as the oxidation of branched-chain amino acids, energy production, and the regulation of metabolic homeostasis. Analysis of Leu-Val metabolites can reveal the specific functions and mechanisms of branched-chain amino acids in cellular energy metabolism, signal transduction, and protein synthesis.

       

      1834434351476625408-TheStructureofLeu-Val.png

      Figure 1. The Structure of Leu-Val

       

      MtoZ Biolabs is proud to present our Leu-Val Analysis Service, built on top of our industry-leading liquid chromatography-mass spectrometry (LC-MS) platform and managed by our team of experienced metabolomics specialists. Our service provides a comprehensive Leu-Val analysis to meet researchers' needs.

       

      Analysis Workflow

       

      1834434418459660288-WorkflowofLeu-ValAnalysisService.PNG

       

      Service Advantages

      • Extensive expertise in handling various biological samples and extracting metabolites.
      • State-of-the-art mass spectrometry platforms.
      • Strict quality control to ensure reliable results.
      • Comprehensive statistical and bioinformatics analysis.
      • Personalized service to meet various research needs.

       

      Applications

      • Discovery of new biomarkers
      • Improvement of disease diagnosis
      • Acceleration of the discovery of innovative therapeutics
      • Unveiling new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. At least 3 materials under identical conditions should be selected for each sample.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Store at -80°C to maintain stability.

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Leu-Val

      4. Raw Data

      5. Custom Analysis Report

       

      Our Leu-Val analysis service is designed to support your research and product development efforts by delivering precise and reliable results. Trust MtoZ Biolabs for all your metabolomics analysis needs.

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