Linoleic Acid Metabolism Service
- Advanced mass spectrometry technology with high sensitivity and accuracy
- Comprehensive data analysis supported by a team of experienced analysts
- Strict quality control to ensure reliable results
- Personalized service to meet various research needs
- Investigating the role of LA metabolism in various diseases.
- Profiling and comparing LA metabolism under different experimental conditions.
- Screening and evaluating potential drug targets or biomarkers related to LA metabolism.
- Type of samples: Plasma, serum, cell, tissue, etc.
- Quantity: At least 200 μl liquid, 1 x 10⁷ cells, or 200 mg tissue.
- Storage and Shipping: Samples should be stored at -80℃ and shipped with dry ice.
Linoleic acid (LA) is an essential polyunsaturated fatty acid belonging to the omega-6 fatty acid family. It plays a crucial role in human physiology, serving as a precursor for the biosynthesis of bioactive lipid mediators, including prostaglandins, leukotrienes, and thromboxanes. These molecules are involved in various physiological and pathological processes, such as inflammation, immune response, and cell signaling. Because the human body cannot synthesize linoleic acid, it must be obtained through dietary sources, including vegetable oils, nuts, and seeds.
The metabolism of linoleic acid involves a series of enzymatic reactions that convert LA into longer-chain and more unsaturated fatty acids, such as gamma-linolenic acid (GLA) and arachidonic acid (AA). This metabolic pathway includes crucial steps such as desaturation and elongation, mediated by enzymes like delta-6-desaturase and elongase. The proper functioning of these metabolic pathways is essential for maintaining the balance of pro-inflammatory and anti-inflammatory eicosanoids, which are derived from these fatty acids.
Research into linoleic acid metabolism is vital for understanding its role in health and disease. Aberrations in this pathway are associated with various conditions, including cardiovascular diseases, inflammatory disorders, and metabolic syndromes. Studying these metabolic processes provides valuable insights into the development of therapeutic strategies targeting these pathways to manage or prevent related diseases.
Services at MtoZ Biolabs
At MtoZ Biolabs, we use state-of-the-art mass spectrometry technology, combined with advanced metabolic profiling techniques, to provide comprehensive analysis of Linoleic Acid metabolism. Our robust platform, comprising UPLC, and MS/MS, ensures accurate identification and quantification of LA metabolites. Our sophisticated bioinformatics tools further aid in data analysis, providing valuable insights into the complex dynamics of LA metabolism.
Analysis Workflow
Service Advantages
Applications
Our Linoleic Acid Metabolism Service is applicable in several research domains, including:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Linoleic Acid Metabolism Analysis
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to offering our clients the most reliable and comprehensive Linoleic Acid Metabolism Service. Contact us today to learn more about how we can assist with your research!
How to order?
