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    Methionine Sulfoxide Analysis Service

      Methionine sulfoxide is an oxidation product of methionine, formed under oxidative stress conditions. As a key biomarker of oxidative stress, methionine sulfoxide plays a significant role in various biological processes, with levels linked to diseases such as neurodegenerative diseases, cardiovascular diseases, and inflammatory disorders. The regulation of methionine sulfoxide involves methionine sulfoxide reductase (MSR), which reduces methionine sulfoxide back to methionine, thereby playing a crucial role in cellular antioxidant defense. Analyzing methionine sulfoxide provides valuable insights for disease prevention, diagnosis, and treatment.

       

       1816026848028119040-MolecularStructureofMethionineSulfoxide.png

      Figure 1. Molecular Structure of Methionine Sulfoxide

       

      MtoZ Biolabs offers Methionine Sulfoxide Analysis Service using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of methionine sulfoxide in complex biological matrices.

       

      Analysis Workflow

       

      1816027362308509696-TheWorkflowofMethionineSulfoxide.png

       

      Experimental Instruments

      • Liquid Chromatography-Mass Spectrometry (LC-MS)
      • Gas Chromatography-Mass Spectrometry (GC-MS)
      • Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

       

      Service Advantages

      • Rapid Analysis Cycle and Cost-Effectiveness
      • Stable, Reliable, and Highly Sensitive Results
      • Comprehensive One-Stop Service for Extensive Testing Needs
      • User-Friendly Operation with Wide Application Scope
      • Supported by Extensive Bioanalytical Resources and Advanced Platforms

       

      Sample Submission Requirements

      Sample Types

      Serum, plasma, urine, tissue homogenates, and other biological samples.

       

      Sample Volume

      At least 200 μL of liquid sample or 200 mg of tissue sample.

       

      Sample Preservation

      Store and transport samples at -80 °C.

       

      Applications

      Assess oxidative stress levels in cells and tissues.

       

      Investigate methionine sulfoxide's role in neurodegenerative diseases.

       

      Study changes in methionine sulfoxide levels in cardiovascular diseases.

       

      Analyze methionine sulfoxide metabolism in inflammatory diseases.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Methionine Sulfoxide

      4. Raw Data

      5. Custom Analysis Report

       

      MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into methionine sulfoxide's extensive physiological roles through top-tier analytical techniques and expert services.

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