Monocrotaline Analysis Service
- High Sensitivity and Accuracy: LC-MS technology can precisely identify and quantify trace components in complex samples.
- Broad Applicability: Suitable for various biological samples, including plant tissues, blood, and urine.
- Rapid Analysis: The process from sample handling to report generation is efficient, shortening the analysis cycle.
- Customized Services: Personalized analysis solutions provided based on specific customer needs.
Monocrotaline (MCT) is a naturally occurring alkaloid predominantly found in the Crotalaria genus. Known for its potent biological activities, MCT offers various pharmacological benefits including anti-inflammatory and anticancer properties. Nonetheless, its potential toxicity poses serious health risks, including severe liver and lung disorders in humans and animals. Precise MCT analysis is essential, not only for unraveling its biological mechanisms but also for advancing pharmaceutical development, ensuring food safety, and enforcing environmental protections.
Figure 1. Molecular Structure of Monocrotaline
MtoZ Biolabs utilizes liquid chromatography-mass spectrometry (LC-MS) for metabolomic analysis of monocrotaline. This technique combines the high separation efficiency of high-performance liquid chromatography (HPLC) with the high sensitivity of mass spectrometry (MS), allowing for the precise detection and quantification of trace components in complex samples. Our services extend beyond identification and quantification to include in-depth studies on the structure-activity relationships, metabolic pathways, and biological activity of alkaloids, providing comprehensive data support.
Analysis Workflow
Services at MtoZ Biolabs
Service Advantages
Sample Submission Requirements
Plant Materials: Generally requires 10-20 g (seeds, leaves, stems).
Biological Samples: Minimum volumes of 0.5 mL for liquids (blood, urine) and 100-500 mg for tissue samples, adjusted as necessary per experimental conditions.
For detailed sample submission instructions, please consult our technical team.
Applications
Drug Development: Assessing the pharmacological potentials and safety profiles of MCT and its analogs.
Environmental Surveillance: Monitoring MCT contamination and evaluating ecological impacts.
Food Safety Assurance: Checking for MCT residues in food products to guarantee consumer safety.
Clinical Insights: Investigating MCT’s metabolic interactions and its implications in disease pathways.
At MtoZ Biolabs, we are dedicated to offering superior metabolomic analysis services for monocrotaline, aimed at enhancing your understanding of its biological functions and assisting in the development and regulatory compliance of associated products. We are eager to support your research endeavors as a trusted scientific partner.
How to order?