Murideoxycholic Acid Analysis Service

Murideoxycholic acid (MDCA) is a secondary bile acid produced primarily in the intestines through the microbial metabolism of primary bile acids secreted by the liver. Structurally, MDCA is a 3α-hydroxy steroid with additional hydroxy groups at the 3 and 6 positions on the cholan-24-oic acid backbone. It acts as a metabolite in both mice and humans and is closely related to cholic acid, being one of its derivatives. MDCA plays a crucial role in the bile acid cycle, regulating the absorption and excretion of bile acids.

 

Research indicates that MDCA is vital not only in normal bile acid metabolism but also in the progression of various diseases, including liver and metabolic disorders. In certain pathological conditions, fluctuations in MDCA levels may serve as critical biomarkers for disease progression and therapeutic response. Therefore, precise detection and analysis of MDCA are essential for a comprehensive understanding of its role in bile acid metabolism, liver function, and related diseases.

 

Figure 1. Molecular Structure of Murideoxycholic Acid

 

MtoZ Biolabs offers Murideoxycholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in MDCA detection.

 

Analysis Workflow

 



 

Service Advantages

• Rapid Analysis Cycle and Cost-Effectiveness
• Stable, Reliable, and Highly Sensitive Results
• Comprehensive One-Stop Service for Extensive Testing Needs
• User-Friendly Operation with Wide Application Scope
• Supported by Extensive Bioanalytical Resources and Advanced Platforms

 

Sample Submission Requirements

Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Murideoxycholic Acid

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into MDCA's extensive physiological roles through top-tier analytical techniques and expert services.