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    N-6-iso-pentenyladenosine-5'-monophosphate Analysis Service

      N-6-iso-pentenyladenosine-5'-monophosphate (iPRMP) is a naturally occurring modified nucleotide that plays a crucial role in various biological processes. Structurally, iPRMP is an adenosine derivative characterized by the addition of an isopentenyl group at the N-6 position of the adenine ring. iPRMP is primarily found in transfer RNAs (tRNAs), where it functions as an essential post-transcriptional modification, enhancing the stability and efficiency of protein synthesis by promoting correct codon-anticodon pairing during translation.

       

      The study of iPRMP has gained significant attention due to its involvement in key cellular processes, including gene expression regulation, cellular differentiation, and stress response mechanisms. Research has shown that alterations in iPRMP levels can impact the overall function of tRNAs, leading to disruptions in protein synthesis and subsequent cellular dysfunction. Additionally, iPRMP has been implicated in the regulation of certain metabolic pathways and has potential links to various diseases, including cancer and neurodegenerative disorders.

       

      1828276525670715392-TheStructureofN-6-iso-pentenyladenosine-5'-monophosphate.png

       

      Figure 1. The Structure of N-6-iso-pentenyladenosine-5'-monophosphate

       

      Analysis Workflow

      At MtoZ Biolabs, we utilize advanced LC-MS/MS technologies to provide a comprehensive analysis of N-6-iso-pentenyladenosine-5'-monophosphate. Our analysis service includes:

      • Sample Preparation
      • Metabolite Extraction
      • LC-MS/MS Analysis
      • Data Processing and Interpretation
      • Report Generation

       

      1828265094334238720-WorkflowforN-6-iso-pentenyladenosine-5'-monophosphateAnalysisService.png

       

      Service Advantages

      • Expertise: A team of professionals specialize in metabolomics and mass spectrometry.
      • Advanced Technology: Utilization of state-of-the-art LC-MS/MS technology for precise and accurate analysis.
      • Data Quality: Ensures high-quality data with comprehensive analysis and stringent quality control measures.
      • Customer Support: Personalized service with continuous customer support during and after the analysis.

       

      Sample Submission Requirements

      1. Sample Types

      • Serum, plasma, urine, tissues, and other biological samples.
      • For each sample, it is necessary to provide a minimum of 3 replicates with the same conditions.

       

      2. Sample Volume

      • A minimum of 200 μL of liquid sample
      • A minimum of 200 mg of tissues

       

      3. Sample Preservation

      Samples should be stored at -80°C to maintain stability.

       

      Note: Please provide detailed information on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on N-6-iso-pentenyladenosine-5'-monophosphate

      4. Raw Data

      5. Custom Analysis Report

       

      With MtoZ Biolabs, you can be assured of reliable, accurate, and professional N-6-iso-pentenyladenosine-5'-monophosphate analysis service. Contact us today to learn more about our services. We look forward to assisting you in your research endeavors!

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