N-Acetylserotonin Analysis Service

N-Acetylserotonin (NAS), also known as Normelatonin, is an intermediate in the biosynthesis of melatonin from tryptophan. It is synthesized from serotonin by the enzyme arylalkylamine N-acetyltransferase (AANAT) and is converted to melatonin by the enzyme acetylserotonin O-methyltransferase (ASMT). NAS is mainly found in the pineal gland, retina, and gastrointestinal tract. In addition to its role in the production of melatonin, NAS has been shown to have potent antioxidant, anti-inflammatory, and neuroprotective properties.

 

N-Acetylserotonin plays a crucial role in the regulation of circadian rhythms and sleep-wake cycles. Irregularities in its production or metabolism can lead to sleep disorders, mood disorders, and various neurological conditions. Furthermore, understanding the biosynthesis and regulation of N-Acetylserotonin can aid in the development of new therapeutics for these conditions.

 



 

Figure 1. The Structure of N-Acetylserotonin

 

MtoZ Biolabs offers the most comprehensive N-Acetylserotonin Analysis Service for our clients, using our advanced metabolomics platform, which combines the latest techniques in mass spectrometry with our expertise in metabolomics. We can help you:

• Identify and quantify N-Acetylserotonin and related metabolites in various biological samples
• Understand the dynamics of N-Acetylserotonin metabolism
• Discover potential biomarkers related to N-Acetylserotonin metabolism

 

Analysis Workflow

 



 

Service Advantages

• Rapid Analysis Cycle and Cost-Effectiveness
• Stable, Reliable, and Highly Sensitive Results
• Comprehensive One-Stop Service for Extensive Testing Needs
• User-Friendly Operation with Wide Application Scope
• Supported by Extensive Bioanalytical Resources and Advanced Platforms

 

Sample Submission Requirements

 



 

• Samples should be stored at -80℃ and shipped with dry ice.
• We recommend providing at least 3 samples of similar conditions for each type of sample.
• Other sample types, please contact us for more details.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on N-Acetylserotonin

4. Raw Data

5. Custom Analysis Report