N4-acetyl-2'-O-methylcytidine Analysis Service
- Extensive experience in various biological sample preparation techniques
- State-of-the-art mass spectrometry platforms
- Professional standard operating procedure
- Highly sensitive and reliable analysis
- Rapid turnaround time
- Competitive pricing
- Customized service
- Studying RNA stability under extreme temperature conditions.
- Epigenetic research related to RNA modifications.
- Investigating RNA modifications in stress response mechanisms.
- Exploring environmental adaptation mechanisms in archaea.
- Assessing RNA modification roles in gene regulation.
N4-acetyl-2'-O-methylcytidine (ac4Cm) is a modified nucleoside and an analog of cytidine. It features both methylation at the 2'-O position of the ribose and acetylation at the N4 position, providing enhanced stability to RNA molecules, particularly under high-temperature conditions. ac4Cm has been predominantly identified in thermophilic archaea, where it plays a crucial role in the organisms’ adaptation to extreme environmental conditions. The dual acetylation and methylation of RNA molecules containing ac4Cm significantly increase their stability, allowing the organisms to maintain functional RNA at elevated temperatures.
Figure 1. The Structure of N4-acetyl-2'-O-methylcytidine
The exploration of ac4Cm and its effects on RNA stability is critical for advancing our understanding of RNA biology, particularly in stress conditions. Moreover, the study of ac4Cm could contribute to the broader understanding of RNA modifications in epigenetics and their potential applications in biotechnology.
Our team at MtoZ Biolabs is equipped with state-of-the-art mass spectrometry instruments and proficient in metabolic profiling and metabolite quantification. We offer a comprehensive N4-acetyl-2'-O-methylcytidine Analysis Service, which can accurately quantify ac4Cm in different types of samples, providing valuable data for your research.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice.
Note: For specific sample submission requirements, please contact our customer service team.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on N4-acetyl-2'-O-methylcytidine
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to providing you with high-quality, efficient, and reliable N4-acetyl-2'-O-methylcytidine Analysis Service. Let's explore the dynamic world of metabolites together!
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