N6-Acetyl-L-Lysine Analysis Service

N6-Acetyl-L-Lysine (N6-Ac-L-Lys) is an acetylated derivative of lysine that plays crucial roles in cellular metabolism, protein function regulation, and signal transduction. It is involved in histone modification, a key factor in regulating gene expression. Changes in N6-Ac-L-Lys levels can be linked to conditions such as cancer, metabolic disorders, and neurodegenerative diseases. Accurate measurement of N6-Ac-L-Lys concentrations provides insights into its biological roles, aiding in the diagnosis and treatment of related conditions.

 

 

Figure 1. Molecular Structure of N6-Ac-L-Lys

 

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of N6-Ac-L-Lys and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of N6-Ac-L-Lys in complex biological matrices.

 

Analysis Workflow

 



 

Service Advantages

 

 

Sample Submission Requirements

Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

 

Sample Volume

At least 200 μL of liquid sample or 200 mg of tissue sample.

 

Sample Preservation

Store and transport samples at -80°C to maintain N6-Ac-L-Lys stability.

 

Applications

Clinical Diagnosis: Measure N6-Ac-L-Lys levels in patients with cancer, metabolic disorders, and neurodegenerative diseases to assist in diagnosis and prognosis.

 

Metabolic Research: Investigate the roles of N6-Ac-L-Lys in cellular metabolism, protein function regulation, and signal transduction.

 

Drug Development: Evaluate the impact of drugs on N6-Ac-L-Lys metabolism to aid in developing new therapeutic agents.

 

Nutritional Research: Analyze the metabolic changes of N6-Ac-L-Lys under different dietary conditions, providing scientific evidence for nutritional regulation and dietary supplementation.

 

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into N6-Ac-L-Lys's extensive physiological roles through top-tier analytical techniques and expert services.