N6-(cis-hydroxyisopentenyl)adenosine Analysis Service

N6-(cis-hydroxyisopentenyl)adenosine (or io6A in short) is a modified nucleoside that is found in the transfer RNA (tRNA) of both eukaryotes and prokaryotes. It plays a key role in the regulation of protein translation. Structurally, io6A is characterized by the addition of a cis-hydroxyisopentenyl group to the N6 position of adenosine. This modification occurs post-transcriptionally and is essential for maintaining the accuracy and efficiency of codon recognition during protein synthesis. Abnormal levels of this molecule have been associated with various diseases, including cancer and neurological disorders. Therefore, the analysis of N6-(cis-hydroxyisopentenyl)adenosine can not only provide insights into disease mechanisms but also aid in the discovery of potential therapeutic targets.

 



 

Figure 1. The Structure of N6-(cis-hydroxyisopentenyl)adenosine

 

At MtoZ Biolabs, we provide comprehensive N6-(cis-hydroxyisopentenyl)adenosine analysis service using cutting-edge analytical platforms with high sensitivity and accuracy. With our state-of-the-art mass spectrometry platform and advanced metabolomics techniques, we can accurately measure the levels of N6-(cis-hydroxyisopentenyl)adenosine in a variety of sample types. Our team of experts will work with you closely to understand your requirements and provide customized solutions.

 

Analysis Workflow

 



 

Service Advantages

• Top-quality service
• Accurate results
• Fast turnaround time
• Advanced technologies
• High accuracy and sensitivity

 

Applications

• Biomarker discovery
• Disease diagnosis and prognosis
• Drug response prediction
• Basic biological research

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. It is necessary to prepare more than 3 biological replicates for each type of sample.

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice.

 

Note: Please provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on N6-(cis-hydroxyisopentenyl)adenosine

4. Raw Data

5. Custom Analysis Report

 

At MtoZ Biolabs, we strive to provide the best quality service to our clients. Contact us today to find out how our N6-(cis-hydroxyisopentenyl)adenosine analysis service can help you advance your research.