N8-Acetylspermidine Analysis Service

N8-Acetylspermidine is a polyamine derivative that plays a crucial role in cell proliferation, differentiation, and gene expression regulation. N8-Acetylspermidine is synthesized from spermidine through an acetylation reaction catalyzed by acetyltransferase. This process is important in the polyamine metabolic pathway, helping maintain cellular homeostasis and regulating various physiological processes.

 

Changes in N8-Acetylspermidine levels are associated with several diseases, such as cancer, neurodegenerative diseases, and metabolic disorders. Quantitative and qualitative analysis of N8-Acetylspermidine and its metabolites can provide deeper insights into their mechanisms in physiological and pathological processes, aiding in disease prevention, diagnosis, and treatment.

 



Figure 1. Molecular Structure of N8-Acetylspermidine

 

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of N8-Acetylspermidine. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of N8-Acetylspermidine in complex biological matrices.

 

Analysis Workflow

 

 

Experimental Instruments

• Liquid Chromatography-Mass Spectrometry (LC-MS)
• Gas Chromatography-Mass Spectrometry (GC-MS)
• Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

 

Service Advantages

 



 

Sample Submission Requirements

Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

 

Sample Volume

At least 200 μL of liquid sample or 200 mg of tissue sample.

 

Sample Preservation

Store and transport samples at -80°C to maintain N8-Acetylspermidine stability.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on N8-Acetylspermidine

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into N8-Acetylspermidine's extensive physiological roles through top-tier analytical techniques and expert services.