Nicotinic Acid Analysis Service

Nicotinic acid, an organic compound with the chemical formula C₆H₅NO₂, is vital for human health. It is synthesized by both plants and animals from the amino acid tryptophan. Dietary sources rich in nicotinic acid include meat, poultry, and specific types of fish such as tuna and salmon. This compound is crucial as a precursor for the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), both of which are involved in DNA repair processes. Additionally, nicotinic acid is used therapeutically as a supplement to treat pellagra, a deficiency disease marked by such clinical manifestations as dermatitis, oral mucosal lesions, anemia, headaches, and fatigue.

 



 

Figure 1. The Structure of Nicotinic Acid

 

Services at MtoZ Biolabs

At MtoZ Biolabs, our Nicotinic Acid Analysis service utilizes state-of-the-art mass spectrometry (MS) technology - a powerful tool known for its sensitivity, specificity, and wide dynamic range. Specifically, we use liquid chromatography-mass spectrometry (LC-MS/MS), a technique that combines the physical separation capabilities of liquid chromatography (LC) with the mass analysis capabilities of MS, to identify and quantify nicotinic acid in your samples.

 

Analysis Workflow

 



 

Service Advantages

• Exceptional Expertise: Our team consists of experts with deep knowledge and experience in mass spectrometry and metabolomics.
• Advanced Technology: We use state-of-the-art LC-MS/MS technology to deliver accurate and reliable results.
• Personalized Service: We offer customizable service options to meet specific research needs.
• Comprehensive Report: Our detailed report provides not only the raw data but also interpretation and insights to help you understand the meaning behind the numbers.

 

Applications

Our Nicotinic Acid Analysis Service is ideal for researchers in fields such as nutrition, metabolism, pharmacology, and disease biology. It can be used to:

• Study the role of nicotinic acid in various metabolic processes.
• Investigate the impact of nicotinic acid deficiency or excess in various health conditions.
• Evaluate the effectiveness of nutritional supplements or drugs containing nicotinic acid.

 

Sample Submission Requirements

• For the Nicotinic Acid Analysis service, we accept various types of samples including plasma, serum, tissue, cells, and urine.
• Please ensure the sample quantity exceeds 0.2 g or 0.2 mL.
• Please keep the samples frozen and ship them on dry ice. 
• Please also include a completed sample submission form with your shipment.

 

Deliverables

1. Experimental Procedures

2. Relevant Mass Spectrometry Parameters

3. Detailed Information on Nicotinic Acid Analysis

4. Mass Spectrometry Images

5. Raw Data

 

At MtoZ Biolabs, we strive to provide the highest quality services to support your research. Contact us today to learn more about our Nicotinic Acid Analysis Service.