Nicotinyl Methylamide Analysis Service
- Qualitative analysis of the metabolites of nicotinyl methylamide
- Quantitative analysis of nicotinyl methylamide content
- Provide a basis for pharmaceutical research and product improvement
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Nicotinyl methylamide is a derivative of nicotinic acid, whose structure closely resembles that of the natural vitamin niacin (vitamin B3). The chemical structure of nicotinyl methylamide includes a methylamide group substituted on the nicotinic acid backbone, a modification that enhances its biological properties and stability, potentially altering its pharmacokinetic profile, such as absorption and distribution within the body.
Metabolomics analysis, utilizing high-throughput techniques such as mass spectrometry and nuclear magnetic resonance, can comprehensively elucidate the metabolic pathways and mechanisms of nicotinyl methylamide within the body. Compared to traditional metabolic analysis methods, metabolomics can detect a broader range of metabolites and concentration changes, providing a more extensive understanding of the compound's metabolic network. Through this approach, both primary and secondary metabolic pathways of nicotinyl methylamide can be identified, including biochemical reactions involving specific enzymes. This helps in understanding the metabolic variations of nicotinyl methylamide in different tissues and organs. Metabolomics analysis can identify various metabolites of nicotinyl methylamide and their structural characteristics, including active metabolites and potentially toxic ones. This is crucial for elucidating its pharmacological effects and toxicological properties. For instance, some metabolites may exhibit greater biological activity or toxicity than the parent compound; metabolomics analysis can help discover these key metabolites and investigate their potential impacts.
Figure 1. The Structure of Nicotinyl Methylamide
MtoZ Biolabs is proud to present our Nicotinyl Methylamide Analysis Service - a cutting-edge offering supported by our advanced liquid chromatography-mass spectrometry (LC-MS) platform and experienced metabolomics team. This service ensures high sensitivity and precision, providing a comprehensive analysis of nicotinyl methylamide.
Analysis Workflow
Service Advantages
1. High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.
2. Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.
3. Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.
4. Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. Please provide more than 3 replicates of each sample type for the analysis.
2. Sample Volume
3. Sample Preservation
Store samples at -80°C to ensure sample stability.
Note: Please provide specific details about sample collection and preparation.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Nicotinyl Methylamide
4. Raw Data
5. Custom Analysis Report
Our Nicotinyl Methylamide Analysis Service is designed to facilitate your research and product development efforts by delivering accurate, reliable, and comprehensive results.
How to order?
