O-Phosphorylethanolamine Analysis Service

O-Phosphorylethanolamine (O-PE) is a crucial organic compound widely found in living organisms. It is a fundamental component of cell membrane phospholipids and plays a significant role in cell signaling and metabolic regulation. O-PE is closely linked to amino acid metabolism, particularly with the metabolism of serine. Phosphorylation of serine generates O-PE, which then contributes to the synthesis of phosphatidylethanolamine (PE), an essential component of cell membranes critical for maintaining cell structure and function.

Abnormal O-PE metabolism is associated with various diseases, including neurodegenerative disorders and metabolic syndromes. Therefore, analyzing O-PE and its metabolites is vital for understanding their functions and mechanisms within the body. Accurate and rapid detection of O-PE levels is invaluable for disease research, drug development, and nutritional science.

 

Figure 1. Molecular Structure of O-PE

 

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of O-PE and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of O-PE in complex biological matrices.

 

Analysis Workflow

 



 

Experimental Instruments

• Liquid Chromatography-Mass Spectrometry (LC-MS)
• Gas Chromatography-Mass Spectrometry (GC-MS)
• Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

 

Service Advantages

 



 

Sample Submission Requirements

 



For detailed sample submission instructions, please consult our technical team.

 

Applications

• Neurodegenerative Disease Research: Investigating the role of O-PE metabolism in Alzheimer's and Parkinson's diseases.
• Metabolic Syndrome Research: Examining changes in O-PE and its metabolites in conditions like obesity and diabetes.
• Drug Efficacy Evaluation: Assessing the impact of drugs on O-PE metabolism and identifying potential therapeutic agents.
• Nutritional Metabolism Research: Studying the effects of diet on O-PE metabolism and its role in nutrient absorption and metabolism.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on O-PE and their Metabolites

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into O-PE's extensive physiological roles through top-tier analytical techniques and expert services.