Olink Protein Detection
Olink protein detection is an innovative, highly sensitive, and high-throughput technology developed by the Swedish company Olink, designed for the precise quantification of thousands of proteins in biological samples. This method is based on the Proximity Extension Assay (PEA), which utilizes DNA-conjugated antibodies to achieve exceptional specificity and sensitivity in protein detection.
Overview of Olink Protein Detection
Olink protein detection employs the PEA technology, where specific antibodies selectively bind to target proteins. Upon successful binding, DNA probes undergo an amplification process, converting protein presence into quantifiable DNA signals. This approach ensures high accuracy and sensitivity, enabling the simultaneous quantification of up to 1,000 proteins in a single sample.
Applications of Olink Protein Detection
Olink protein detection has extensive applications in biomedical research. It facilitates the investigation of protein involvement in disease pathogenesis, progression, and therapeutic response, providing valuable insights for drug discovery and preventive medicine. Furthermore, this technology is increasingly utilized in clinical diagnostics, enabling precise disease classification, staging, and treatment outcome assessment.
Advantages of Olink Protein Detection
1. Exceptional Sensitivity and Specificity
The PEA technology ensures outstanding sensitivity and specificity, allowing for the precise quantification of proteins even at extremely low concentrations.
2. High-Throughput Capabilities
Olink protein detection enables the simultaneous measurement of up to 1,000 different proteins per sample, making it highly suitable for large-scale proteomic studies.
3. Broad Sample Compatibility
This technology is applicable to both liquid and tissue samples, significantly expanding its usability across various research and clinical settings.
4. Quantitative and Data-Driven Analysis
The results are generated as high-resolution digital datasets, facilitating robust statistical analysis and cross-sample comparisons.
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider.
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