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    One Carbon Metabolism Analysis

      One-carbon units are single carbon atoms that are transferred between molecules in various biochemical reactions within the cell. These units are essential in numerous metabolic processes, where they participate in the synthesis and modification of biomolecules, such as nucleotides, amino acids, and lipids. One Carbon Metabolism refers to a network of biochemical reactions that transfer one-carbon units through various enzymatic processes. This pathway is fundamental to several critical cellular functions, including DNA and RNA synthesis, amino acid metabolism, and the methylation of proteins, lipids, and nucleic acids. One Carbon Metabolism is also essential for the production of vital cofactors, such as methionine and folate, which play significant roles in cellular growth, repair, and epigenetic regulation. Dysregulation of this pathway has been linked to numerous health conditions, including cancer, cardiovascular diseases, and neurological disorders, making it a key focus area in biomedical research.

       

      MtoZ Biolabs offers a specialized One Carbon Metabolism Analysis service. Our One Carbon Metabolism Analysis service is based on the principles of mass spectrometry (MS), an analytical technique that measures the mass-to-charge ratio of ions. By combining ultra-performance liquid chromatography (UPLC) with tandem mass spectrometry (MS/MS), our analysis provides a comprehensive profile of one carbon metabolism intermediates including methionine, homocysteine, S-adenosyl methionine, S-adenosyl homocysteine, and several folate derivatives.

       

      Analysis Workflow

       

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      Service Advantages

      • Advanced LC-MS equipment with high sensitivity and accuracy
      • Comprehensive data analysis supported by a team of experienced analysts
      • Strict quality control to ensure reliable results
      • Personalized service to meet various research needs

       

      Sample Submission Requirements

      • Type of samples: Animal tissue, biological fluids, cells, plants, and more.
      • Quantity: At least 10 μl liquid, 1 x 10⁶ cells, or 20 mg solid.

      For specific sample submission requirements, please contact our customer service team.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on One Carbon Metabolism Analysis

      4. Raw Data

      5. Custom Analysis Report

       

      For more information about our One Carbon Metabolism Analysis service, please feel free to contact us. Our team is dedicated to providing you with the most professional and reliable services.

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