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    Organic acids

      Organic acids are carboxylic acids that play crucial roles in various metabolic processes in organisms. They are involved in the TCA cycle, fatty acid oxidation, amino acid metabolism, urea cycle, and many other metabolic pathways. Due to their central role in metabolism, they are often used as biomarkers for various diseases and metabolic disorders.

       

      At MtoZ Biolabs, we offer targeted metabolomics services for the analysis of organic acids. With our advanced LC-MS/MS platform, we are able to provide comprehensive profiling and accurate quantification of organic acids in a variety of biological samples.

       

      Analysis Workflow

      1. Sample Preparation: Depending on the sample type, different extraction methods are applied to efficiently extract organic acids while minimizing degradation.

       

      2. LC-MS/MS Analysis: Samples are analyzed using our state-of-the-art LC-MS/MS platform, which provides high sensitivity, accuracy, and reproducibility.

       

      3. Data Analysis: We perform peak identification, calibration, and quantification of organic acids, followed by statistical and bioinformatics analysis to identify potential biomarkers and metabolic pathways.

       

      4. Comprehensive report with results and interpretation

       

      organic-acids-analysis1

      Figure 1. Workflow of Organic Acid Analysis by HPLC-MS/MS

       

      Service Advantages

      • Experts in Metabolomics: Our team is highly experienced in the field of metabolomics, with a deep understanding of both the technical aspects and biological interpretation.
      • Cutting-edge Technology: We use the latest LC/MS/MS platform for organic acids analysis, ensuring high accuracy and sensitivity.
      • Comprehensive Analysis: We provide a full range of organic acids analysis, covering a wide range of metabolic pathways.
      • Customized Service: Our services can be tailored to meet your specific research needs.

       

      Applications

      • Disease Biomarker Discovery
      • Drug Metabolism Studies
      • Nutritional Research
      • Environmental Toxicology

       

      Sample Submission Requirements

      • Serum/Plasma: 200 μL
      • Urine: 2 mL
      • Animal Tissue: 100 mg
      • Plant Tissue: 200 mg
      • Faeces: 200 mg


      For other sample types and dosages, please contact our sales.


      Sample transport: Based on 3-4 kg of dry ice evaporating in one day, please use a sufficient amount of dry ice for transport (it is recommended to use larger pieces of dry ice, as large pieces of dry ice evaporate slower) and close it with a foam box. And try to use faster postal service to reduce the possibility of sample degradation during transport. Please feel free to contact us if you need any further assistance.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Organic Acids

      4. Mass Spectrometry Images

      5. Raw Data

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