Oxidative Phosphorylation Analysis Service
- Comprehensive: Our service provides a comprehensive profile of oxidative phosphorylation, covering all major metabolites in the pathway.
- Accurate: With our advanced mass spectrometry techniques, we can accurately measure the abundance of each metabolite.
- Quality Assurance: All services are performed by highly experienced staff and undergo stringent quality control.
- Fast Turnaround Time: We understand the importance of time in research and strive to provide the results in the fastest time possible.
- Metabolic pathway analysis: Understanding the changes in oxidative phosphorylation can shed light on the metabolic alterations in diseases.
- Drug discovery: The information obtained can be used to identify potential drug targets.
- Disease diagnosis and prognosis: Changes in oxidative phosphorylation can be used as biomarkers for disease diagnosis and prognosis.
- Type of samples: Plasma, serum, cell, tissue, etc.
- Quantity: At least 500 μl liquid, 1 x 10⁷ cells, or 200 mg tissue.
- Storage and Shipping: Samples should be stored at -80℃ and shipped with dry ice.
- Note: Avoid repeated cycles of freezing and thawing
Oxidative phosphorylation is the final and critical stage of cellular respiration, primarily occurring within the mitochondria. This process is pivotal in the production of ATP, the universal energy currency of cells, by harnessing the energy released during the electron transport chain to power the synthesis of ATP from ADP and inorganic phosphate. It is intricately linked to the metabolic function and energy balance of cells, and its efficiency directly impacts cellular health, aging, and overall organism vitality. Studying oxidative phosphorylation is crucial for a deeper understanding of metabolic diseases, such as diabetes and various mitochondrial disorders. It is also essential in cancer research, where altered metabolic pathways play a key role in tumor growth and survival.
Figure 1. Schematic Representation of Oxidative Phosphorylation in Mitochondria
Utilizing advanced liquid chromatography-mass spectrometry (LC-MS) techniques, MtoZ Biolabs can accurately separate and identify various metabolites, providing precise information on its molecular weight and structure. For quantitative analysis, we employ high-performance liquid chromatography (HPLC) with ultraviolet-visible (UV-Vis) detection to determine its content in various samples, helping to study its distribution and metabolism in different biological systems.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
For detailed information on sample submission, please contact our customer service team.
Deliverables
1. Experimental Procedures
2. Relevant HPLC and Mass Spectrometry Parameters
3. Detailed Information on Oxidative Phosphorylation Analysis
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to providing the best quality service to advance your research. For more information, feel free to contact us.
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