Oxysterols

Oxysterols are oxygenated derivatives of cholesterol, and they play pivotal roles in numerous biological processes, such as cholesterol homeostasis, immune response, and apoptosis. Due to their significance, the study of oxysterols has been of great interest to scientists in the fields of medical and biological research. At MtoZ Biolabs, we offer comprehensive targeted metabolomics services for oxysterols, using advanced HPLC-MS/MS platforms.

Yanagisawa, R. et al. Int. J. Mol. Sci. 2022.

Figure 1. The major pathway for Oxysterol synthesis and Its Regulatory Effect

Analysis Workflow

1. Sample Preparation: This involves extraction of oxysterols from different types of samples.

2. HPLC-MS/MS Analysis: The extracted samples are then analyzed using our advanced HPLC-MS/MS platforms. This allows for high-throughput and high-sensitivity detection of oxysterols.

3. Data Analysis: The generated data is then analyzed by our team of experts to identify and quantify oxysterols.

Service Advantages

• We use advanced HPLC-MS/MS platforms for high-throughput and high-sensitivity detection.
• Our team of experts is experienced in data analysis and interpretation.
• We offer personalized data reports tailored to meet your research needs.

Applications

• Drug Discovery and Development
• Biomarker Discovery
• Metabolic Pathway Research

Sample Submission Requirements

• 200 μL plasma
• 100 mg tissue

Deliverables

1. Experimental Procedures

2. Relevant Mass Spectrometry Parameters

3. Detailed Information on Oxysterols

4. Mass Spectrometry Images

5. Raw Data

Samples should be flash frozen in liquid nitrogen and stored at -80℃, and shipped on dry ice. For other types of samples and volumes, please contact us.

At MtoZ Biolabs, we are dedicated to providing you with the most reliable and comprehensive oxysterols targeted metabolomics service. Contact us today to discuss your project needs.