Peanut Agglutinin (PNA) Analysis Service
- Biomarker Discovery: Identification of abnormal glycosylation patterns associated with diseases.
- Clinical Diagnostics: Detection of PNA levels can be useful for diagnosing certain conditions.
- Biological Research: Studying the roles of PNA in cellular processes.
- Type of samples: Plasma, serum, cell, tissue, etc.
- Quantity: At least 200 μl liquid, 1 x 10⁷ cells, or 200 mg tissue.
Peanut Agglutinin (PNA) is a plant lectin protein derived from the peanut plant (Arachis hypogaea). PNA has a high affinity for a particular carbohydrate motif, Gal-β(1-3)-GalNAc, which can be found in a variety of glycoconjugates. Due to its specificity, PNA is widely used in biological research for studying cell surface carbohydrates, glycoconjugate distribution, and cell-cell interactions. It can also be used as a diagnostic tool for detecting abnormalities in glycosylation associated with diseases such as cancer.
Figure 1. Peanut Agglutinin Complexed with a Di-galactose
In our PNA analysis service, we utilize advanced mass spectrometry-based techniques, including liquid chromatography-mass spectrometry (LC-MS) and tandem mass spectrometry (MS/MS), to effectively identify and quantify PNA. This involves the extraction of PNA from samples, enzymatic or chemical derivatization to improve detection, separation of PNA using high performance liquid chromatography (HPLC), and finally, mass spectrometric analysis for detailed characterization.
Analysis Workflow
Applications
PNA analysis service can be applied in various fields, including:
Sample Submission Requirements
For more details, please feel free to get in touch with our customer service team.
Deliverables
1. Experimental Procedures
2. Relevant Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Peanut Agglutinin Analysis
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are dedicated to providing high-quality, reliable, and comprehensive analysis services. Contact us today to learn more about our Peanut Agglutinin (PNA) Analysis Service.
How to order?
