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    Pentose and Glucuronate Interconversions Metabolism Service

      The interconversion of pentoses and glucuronate is a critical metabolic pathway in carbohydrate metabolism, involving the transformation of pentose sugars and glucuronate (along with their respective salts or esters). Pentoses, which arise from the degradation of nucleotides and other biomolecules, are vital for nucleotide biosynthesis and the maintenance of cellular energy balance. Glucuronate, a derivative of glucose, acts as a precursor in the synthesis of glycosaminoglycans and other crucial biomolecules.

       

      This pathway encompasses a series of enzymatic reactions integral to processes such as gluconeogenesis, transamination, deamination, and lipogenesis. Abnormalities in the interconversion of pentoses and glucuronate have been linked to various pathological conditions, including rare disorders such as familial tumoral calcinosis. A comprehensive understanding of the dynamic changes within this metabolic pathway is essential for elucidating the molecular mechanisms underlying diverse physiological and pathological states.

       

      Services at MtoZ Biolabs

      Pentose and glucuronate interconversions are integral to the metabolic process, contributing to the generation and disposition of carbohydrates in living organisms. They involve pentoses (five-carbon sugars) and glucuronates (derivatives of glucose), which undergo a series of enzymatic reactions, leading to the production of important biomolecules.

       

      We employ advanced mass spectrometry-based metabolomics, combined with robust bioinformatics analysis, to present a comprehensive view of these metabolic processes. Our technology allows us to identify and quantify multiple metabolites involved in pentose and glucuronate interconversions, thus providing valuable insights into metabolic pathways and disease mechanisms.

       

      Analysis Workflow

       

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      Service Advantages

      We pride ourselves on our:

      • Expertise: Our team of experts is well-versed in metabolomics and mass spectrometry.
      • Advanced Techniques: We utilize cutting-edge technologies to deliver high-quality results.
      • Comprehensive Analysis: We offer deep insights into pentose and glucuronate interconversions.
      • Tailored Service: We provide a personalized service based on individual project needs.

       

      Applications

      This service is valuable in:

      • Understanding the role of pentose and glucuronate interconversions in disease.
      • Discovering new drug targets.
      • Biomarker identification and validation.
      • Investigating the effects of drugs or treatments on these metabolic pathways.

       

      Sample Submission Requirements

      • We accept various types of samples including plasma, serum, tissue, cells, and urine.
      • Please ensure your submitted sample surpasses 0.5 g or 0.5 mL.
      • Samples should be stored in a -80℃ environment and transported on dry ice.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Pentose and Glucuronate Interconversions Metabolism Analysis

      4. Mass Spectrometry Images

      5. Raw Data

       

      At MtoZ Biolabs, we are dedicated to providing high-quality services to accelerate your research. For further details or inquiries about our Pentose and Glucuronate Interconversions Metabolism Service, please feel free to contact us. We look forward to partnering with you on your research journey!

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