Molecular Weight Analysis
- High Precision: Especially with mass spectrometry, which offers extremely high accuracy in molecular weight determination.
- High Sensitivity: Capable of detecting low-abundance biomolecules.
- Versatility: Applicable to various biomolecules, including proteins, nucleic acids, and polysaccharides.
The molecular weight of a biological product is the total mass of all its constituent atoms, typically expressed in Daltons (Da) or kilodaltons (kDa), where 1 Da equals the mass of a hydrogen atom. Molecular weight analysis of biological products, such as proteins, antibodies, and nucleic acids, is a critical technique that provides essential structural information and quality control parameters for research and development. This analysis can determine the exact mass of a biomolecule and distinguish between different forms, such as monomers, dimers, and aggregates. Additionally, it can detect impurities or polymorphisms within a sample. When combined with other analytical techniques, such as mass spectrometry, it can provide primary structural information about the biomolecule.
Services at MtoZ Biolabs
Molecular weight analysis is crucial for revealing the fundamental structural characteristics and stability of biological products. It is an indispensable step in quality control and product development, ensuring the safety and efficacy of biological products. MtoZ Biolabs offers various methods to analyze the molecular weight of different biological products, covering almost all types. These methods include gel permeation chromatography (GPC) for separating and analyzing high molecular weight compounds, SDS-PAGE electrophoresis for separating proteins by molecular weight differences, and mass spectrometry (MS) for high-precision molecular weight determination and structural information.
Service Advantages
Applications
1. Product Consistency Verification: Ensures batch-to-batch consistency.
2. Structural Change Detection: Identifies and monitors structural changes during storage and use.
3. Regulatory Submission Support: Provides necessary structural and purity data for drug submissions.
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Molecular Weight of Biopharmaceuticals
4. Mass Spectrometry Images
5. Raw Data
Molecular weight analysis is a core technology in the research and development of biological products. Its accuracy and reliability are vital for ensuring the quality and safety of these products. MtoZ Biolabs' molecular weight analysis services can precisely determine the molecular weight of nearly all types of biological products, aiding researchers in their studies. For consultation on our services, please contact us.
How to order?
