Procyanidin A1 Analysis Service
- High-Performance Liquid Chromatography (HPLC): For separating and quantifying different types of proanthocyanidins.
- Mass Spectrometry (MS): Combined with HPLC to provide molecular weight and structural information of proanthocyanidins.
- Nuclear Magnetic Resonance (NMR): For detailed molecular structure analysis of proanthocyanidins.
- Spectroscopy (e.g., UV-Vis and FTIR): For preliminary identification and quantitative analysis.
Polyphenols are the largest group of secondary metabolites in plants, and their structural determination has been a focal point in research. Among polyphenols, procyanidin, also known as condensed tannins, are derived from proanthocyanidins. Procyanidin and proanthocyanidins are ubiquitously present in the plant kingdom and are commonly found in varying concentrations in everyday foods such as fruits, vegetables, legumes, grains, and nuts, as well as in cosmetics and pharmaceuticals containing plant materials. As natural antioxidants, procyanidins are used to stabilize food color, prevent rancidity caused by the oxidation of unsaturated fats, and for the chemoprevention of various degenerative tumors. Besides their antioxidant properties, procyanidin have reported anticancer, anti-infection, anti-inflammatory, cardioprotective, antibacterial, antimutagenic, wound healing, antidiabetic, and antiallergic activities.
Procyanidin A1 is a dimer composed of two catechin or epicatechin units linked by an A-type bond (C4-C8 or C2-O7), commonly found in grape seeds, pine bark, and red wine. It exhibits strong antioxidant, antibacterial, antiviral, and anticancer properties and is widely utilized in health products and cosmetics for skin protection and anti-aging. MtoZ Biolabs offers comprehensive qualitative and quantitative analysis services for procyanidin A1, supporting researchers and institutions in their detailed studies of this compound.
Figure 1. The Structure of Procyanidin A1
Services at MtoZ Biolabs
1. Detectable Procyanidins at MtoZ Biolabs
2. Procyanidins Analysis Techniques
3. Procyanidin A1 Targeted Metabolomics Analysis
Figure 2. The Workflow of Targeted Metabolomics for Procyanidin A1
Applications
1. Antioxidant Activity: Procyanidin A1 effectively scavenges free radicals in the body, slowing the aging process and preventing various chronic diseases.
2. Anti-inflammatory Activity: It reduces inflammatory responses and may be used to treat inflammation-related diseases such as arthritis and cardiovascular diseases.
3. Anticancer Potential: Studies indicate that procyanidin A1 has potential in preventing and treating certain cancers by inducing apoptosis and inhibiting cancer cell proliferation.
4. Cardiovascular Health: It improves vascular function, lowers blood pressure and cholesterol levels, aiding in the prevention of cardiovascular diseases.
5. Neuroprotection: Procyanidin A1 shows potential protective effects in the prevention and treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
Proanthocyanidins, oligomeric compounds composed of catechin and epicatechin monomers, are widely present in food and hold significant medicinal value. Utilizing the LC-MS technology platform, MtoZ Biolabs provides qualitative, quantitative and metabolic analysis of procyanidin A1 with exceptional sensitivity, reproducibility, and accuracy, expanding the research on its biological activities and medicinal value.
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Procyanidin A1 Analysis
4. Mass Spectrometry Images
5. Raw Data
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