Procyanidin B1 Analysis Service
- High-Performance Liquid Chromatography (HPLC): For separating and quantifying different types of proanthocyanidins.
- Mass Spectrometry (MS): Combined with HPLC to provide molecular weight and structural information of proanthocyanidins.
- Nuclear Magnetic Resonance (NMR): For detailed molecular structure analysis of proanthocyanidins.
- Spectroscopy (e.g., UV-Vis and FTIR): For preliminary identification and quantitative analysis.
Polyphenols are the largest group of secondary metabolites in plants, and their structural determination has been a focal point in research. Among polyphenols, procyanidin, also known as condensed tannins, are derived from proanthocyanidins. Procyanidin and proanthocyanidins are ubiquitously present in the plant kingdom and are commonly found in varying concentrations in everyday foods such as fruits, vegetables, legumes, grains, and nuts, as well as in cosmetics and pharmaceuticals containing plant materials. As natural antioxidants, procyanidins are used to stabilize food color, prevent rancidity caused by the oxidation of unsaturated fats, and for the chemoprevention of various degenerative tumors. Besides their antioxidant properties, procyanidin have reported anticancer, anti-infection, anti-inflammatory, cardioprotective, antibacterial, antimutagenic, wound healing, antidiabetic, and antiallergic activities.
Procyanidin B1 is a dimer composed of two catechin units connected via B-type bonds (C4-C8). This compound is commonly present in grape seeds, apples, chocolate, and tea leaves. It exhibits a range of biological activities, such as antioxidative, antiviral, antibacterial, and cardioprotective effects. Procyanidin B1 is utilized in nutritional supplements, as a food additive, and in pharmaceutical development. MtoZ Biolabs offers both qualitative and quantitative analysis services for Procyanidin B1, aiding researchers and scientific institutions in the comprehensive study of this compound.
Figure 1. The Structure of Procyanidin B1
Services at MtoZ Biolabs
1. Detectable Procyanidins at MtoZ Biolabs
2. Procyanidins Analysis Techniques
3. Procyanidin B1 Targeted Metabolomics Analysis
Applications
1. Antidiabetic
Liu, Z. et al. Foods. 2024.
3. Anti-inflammation
Xing, J. et al. Mol Cell Biochem. 2015.
Proanthocyanidins, oligomeric compounds composed of catechin and epicatechin monomers, are widely present in food and hold significant medicinal value. Utilizing the LC-MS technology platform, MtoZ Biolabs provides qualitative and quantitative analysis of procyanidin B1 with exceptional sensitivity, reproducibility, and accuracy, expanding the research on its biological activities and medicinal value.
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Procyanidin B1 Analysis
4. Mass Spectrometry Images
5. Raw Data
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