Progesterone Analysis Service

Progesterone (P4) is a key steroid hormone secreted primarily by the corpus luteum of the ovary and the adrenal cortex. It plays a crucial role in regulating the menstrual cycle, maintaining pregnancy, and supporting embryonic development. P4 levels are critical indicators for evaluating luteal function, pregnancy status, and various hormone-related disorders, including infertility and endometriosis. Additionally, P4 contributes to immune regulation, bone density maintenance, and central nervous system function. As a major progestogen, P4 also serves as an essential metabolic intermediate in the synthesis of other steroid hormones, such as sex hormones and corticosteroids, and it functions as a neurosteroid, influencing brain activity. Therefore, accurate measurement of P4 is vital for both clinical diagnostics and research applications.

 



Figure 1. Molecular Structure of Progesterone

 

MtoZ Biolabs offers Progesterone Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in P4 detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

Detects very low concentrations of P4 accurately.

 

2. High Specificity

Differentiates P4 from other compounds using mass spectrometry.

 

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

 

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

 

5. Versatility

Capable of analyzing P4 and its related metabolites.

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, etc.

 

2. Sample Volume

At least 200 μL of liquid sample or 200 mg of solid sample.

 

3. Sample Preservation

Store samples at -20°C or lower to prevent degradation, avoiding repeated freeze-thaw cycles.

 

Note: Provide details on sample collection and handling.

 

Applications

1. Clinical Diagnosis: Assessment of luteal function, diagnosis of infertility, and evaluation of endometriosis and other gynecological conditions.

 

2. Pregnancy Monitoring: Monitoring pregnancy status and luteal function, aiding in early pregnancy evaluation.

 

3. Research Applications: Providing data for biomedical research to better understand P4's role in various physiological and pathological conditions.

 

4. Hormone Level Assessment: Evaluating P4 levels for guiding hormone therapy and intervention.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Progesterone

4. Raw Data

5. Custom Analysis Report

 

Our Progesterone Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.