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    Propanoate Metabolism Service

      The propanoate metabolism pathway is a key biochemical process involving the conversion and utilization of propanoate in humans and other organisms. Propanoate can be transformed into various metabolic intermediates, playing a crucial role in energy metabolism and fatty acid synthesis. This pathway is essential for maintaining metabolic balance and cellular function.

       

      Key enzymatic in this pathway include:

      1. Propionyl-CoA Carboxylase (PCC): Catalyzes the conversion of propionyl-CoA to methylmalonyl-CoA.
      2. Methylmalonyl-CoA Mutase (MCM): Converts methylmalonyl-CoA into succinyl-CoA. This reaction requires vitamin B12 as a coenzyme.
      3. Succinyl-CoA Synthase: Incorporates succinyl-CoA into the tricarboxylic acid cycle (TCA cycle), contributing to energy production.

       

      Understanding these enzymes and their roles in propanoate metabolism is critical for diagnosing and treating metabolic disorders. Additionally, this pathway provides potential therapeutic targets for drug development. At MtoZ Biolabs, we offer Propanoate Metabolism Service to researchers and enterprises globally to help them gain in-depth understanding of this fundamental process which impacts organism's physiology and pathology.

       

      Services at MtoZ Biolabs

      MtoZ Biolabs is committed to delivering top-tier, technically rigorous, and scientifically robust services in metabolomics and mass spectrometry. We are a team of experts with extensive experience in the field of metabolomics and biochemical pathway analysis. Propanoate metabolism is analyzed by using high-resolution mass spectrometry techniques, specifically HPLC-MS. This method provides high sensitivity and specificity for the identification and quantification of metabolites involved in propanoate metabolism.

       

      Analysis Workflow

       

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      Service Advantages

      • Expertise: Our team has deep expertise in both mass spectrometry and metabolomics, enabling us to provide you with highly accurate data.
      • Advanced Technology: We use state-of-the-art HPLC-MS technique for high-resolution analysis.
      • Strict Quality Control: We adhere to strict quality control procedures to ensure the reliability of our results.
      • Data Analysis: Our bioinformatics team provides a detailed interpretation of the data, assisting you in understanding the biological implications of the findings.

       

      Sample Submission Requirements

      • We accept various types of samples including plasma, serum, tissue, cells, and urine.
      • Please ensure your submitted sample surpasses 0.5 g or 0.5 mL.
      • Samples should be stored in a -80℃ environment and transported on dry ice.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Propanoate Metabolism Analysis

      4. Mass Spectrometry Images

      5. Raw Data

       

      At MtoZ Biolabs, our focus is not just delivering results; it's delivering insights that can push your research forward. Partner with us today to explore the secrets of propanoate metabolism.

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