Protein content is a crucial quality control parameter in biopharmaceuticals, impacting drug efficacy, dosage, and production efficiency. Accurate determination of protein content is vital for controlling residual impurities. Amino acid analysis (AAA) determines protein content based on its amino acid composition. This method hydrolyzes protein samples into amino acids, which are then quantified using high performance liquid chromatography (HPLC). This technique avoids interference from other components, ensuring high accuracy and reliability, and can be applied to proteins of any source and properties.
Figure 1. Workflow for Protein Content Determination Based on AAA
MtoZ Biolabs has developed a protein content determination platform using high-resolution liquid chromatography and amino acid analysis. We provide precise and reliable measurements of protein content and analyze the proportions of various amino acids within proteins. This service supports a wide range of needs in biopharmaceutical development, quality control, and research, offering substantial assistance for both scientific and commercial endeavors. Free project evaluation!
Deliverables
In the technical report, MtoZ Biolabs will provide you with detailed technical information, including:
1. Experimental Procedures
2. Relevant Chromatographic Parameters
3. Comprehensive Details on Protein Content Determination via Amino Acid Analysis
4. Chromatographic Images
5. Raw Data