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    Pyrrole Analysis Service

      Pyrrole is a five-membered aromatic heterocyclic compound with the molecular formula C₄H₅N. It consists of a ring structure made up of four carbon atoms and one nitrogen atom, with two double bonds contributing to its aromaticity. The nitrogen atom has a lone pair of electrons, which participates in the aromatic π-electron cloud, making pyrrole a highly conjugated and electron-rich compound. Due to its aromaticity and electron-rich nature, pyrrole is present in many pharmaceutical compounds. Its derivatives exhibit a wide range of biological activities, such as anti-inflammatory, antimicrobial, antitumor, and antiviral effects. The pyrrole ring is found in various drug molecules, including non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics, and anticancer agents.

       

      Changes in the levels of pyrrole and its metabolites in the body may reflect specific disease states. Because pyrrole is a structural unit of many important biological molecules, such as heme, chlorophyll, and vitamin B12, abnormal levels of its metabolites may be associated with various health issues, including blood disorders (such as anemia), liver diseases (such as cirrhosis), and other metabolic disorders. Therefore, analyzing the levels of pyrrole and its metabolites can serve as potential biomarkers for these diseases, aiding in early diagnosis, monitoring disease progression, and evaluating treatment efficacy. The metabolites of pyrrole may also reflect levels of oxidative stress in the body. The oxidation of the pyrrole structure can produce various toxic products that can cause damage by reacting with cellular components. By monitoring the levels of pyrrole and its metabolites, it is possible to assess the degree of oxidative stress, thereby helping to develop targeted therapeutic and preventive measures.

       

      1834435287058075648-TheStructureofPyrrole.png

      Figure 1. The Structure of Pyrrole

       

      At MtoZ Biolabs, we provide a top-notch Pyrrole Analysis Service, leveraging our industry-leading liquid chromatography-mass spectrometry (LC-MS) platform and a seasoned team of metabolomics experts. Our service offers a detailed analysis of pyrrole to meet researchers' needs.

       

      Analysis Workflow

       

      1834435325641478144-WorkflowofPyrroleAnalysisService.PNG

       

      Service Advantages

      • Extensive expertise in handling various biological samples and extracting metabolites.
      • State-of-the-art mass spectrometry platforms.
      • Strict quality control to ensure reliable results.
      • Comprehensive statistical and bioinformatics analysis.
      • Personalized service to meet various research needs.

       

      Applications

      • Identification of new disease biomarkers
      • Improvement of disease diagnosis
      • Acceleration of innovative therapeutics discovery
      • Revelation of new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. At least 3 samples under the same conditions are required for each material category. 

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Store at -80°C to ensure stability.

       

      Note: Please provide detailed information on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Pyrrole

      4. Raw Data

      5. Custom Analysis Report

       

      With our Pyrrole Analysis Service, we aim to support your research and product development efforts by delivering accurate and reliable results. Trust MtoZ Biolabs for all your metabolomics analysis needs.

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