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    Pyruvate Analysis Service

      Pyruvate is a central metabolite in cellular metabolism, serving as a critical junction in various metabolic pathways, including glycolysis, the tricarboxylic acid (TCA) cycle, and fermentation processes. It plays a pivotal role in energy production, biosynthesis, and metabolic regulation. Pyruvate can be converted into acetyl-CoA for entry into the TCA cycle, lactate in anaerobic conditions, or used in gluconeogenesis, highlighting its versatility in cellular metabolism. The analysis of pyruvate levels and fluxes is essential for understanding metabolic health, diagnosing metabolic disorders, and developing therapeutic interventions for conditions like diabetes, cancer, and mitochondrial diseases. MtoZ Biolabs offers a specialized Pyruvate Analysis Service utilizing advanced mass spectrometry techniques to accurately quantify and analyze pyruvate and its metabolic pathways. 

       

      1818131404270718976-TheStructureofPyruvate.png

       

      Figure 1. The Structure of Pyruvate

       

      Services at MtoZ Biolabs

      At MtoZ Biolabs, using state-of-the-art mass spectrometry technology, we provide precise, reliable, and cost-effective analyses of various metabolites including pyruvate. Our Pyruvate Analysis Service is based on high-performance liquid chromatography (HPLC) platforms, a powerful tool for the analysis of metabolites in complex samples. This technique allows for the highly sensitive and specific detection of pyruvate, as well as the ability to quantify its concentration in various biological samples.

       

      Analysis Workflow

       

      1818127260885569536-WorkflowforPyruvateAnalysisService.png

       

      Service Advantages

      • Advanced HPLC-MS equipment with high sensitivity and accuracy
      • Comprehensive data analysis supported by a team of experienced analysts
      • Strict quality control to ensure reliable results
      • Personalized service to meet various research needs

       

      Applications

      Pyruvate Analysis Service could be applied in various scenarios, including but not limited to:

      • Metabolic pathway research
      • Disease biomarker discovery
      • Drug metabolism studies
      • Nutritional and environmental exposure assessment

       

      Sample Submission Requirements

      For optimal results, please follow these guidelines for sample submission:

      • For biofluids, we recommend using no less than 200 μl of sample.
      • For tissue samples, please provide at least 200 mg of tissue.
      • Samples should be stored in a -80℃ environment and transported on dry ice.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Pyruvate Analysis

      4. Mass Spectrometry Images

      5. Raw Data

       

      For more details on our Pyruvate Analysis Service, or any other services, please feel free to contact us at MtoZ Biolabs. We look forward to serving your research needs.

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