Resources
Proteomics Databases
Metabolomics Databases
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• Molecular and Cellular Proteomics
Molecular and Cellular Proteomics is a scientific discipline that investigates the composition, structure, function, and dynamic changes of proteins within living systems. Its goal is to uncover the mechanisms through which proteins function at the molecular and cellular levels. As a cutting-edge field in life sciences, it integrates mass spectrometry, advanced separation techniques, and bioinformatics, providing powerful tools for probing complex biological systems. By analyzing the expression profil......
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Bottom up proteomics is a widely used strategy for qualitative and quantitative analysis of proteins in proteomics research. Unlike top-down proteomics, the core principle of bottom up proteomics involves digesting the entire protein sample into smaller peptides prior to analysis. These peptides are then analyzed in detail by mass spectrometry (MS). This process allows for the precise investigation of protein structure, function, and dynamic changes, facilitating the efficient analysis of thousands of......
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Single-cell proteomics (SCP) is a cutting-edge analytical technique that deciphers protein composition and function at the resolution of individual cells. By uncovering cellular-level details, single-cell proteomics reveals intercellular heterogeneity and addresses limitations of traditional bulk proteomics, which provide only average or aggregate protein expression data. In plant research, single-cell proteomics circumvents challenges posed by rigid cell walls that hinder traditional methods from acc......
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• Quantitative Mass Spectrometry
Quantitative mass spectrometry is primarily employed to measure the concentrations of proteins or other molecular components in biological samples, providing insights into their roles in specific biological processes or disease states. This technique utilizes a mass spectrometer to analyze the mass, abundance, and other characteristics of target molecules with high sensitivity. By integrating standardized quantitative methods, it enables precise measurement of molecular information in complex biologic......
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CD spectroscopy of proteins is a versatile and widely used technique for investigating the conformational and dynamic properties of biological macromolecules. By measuring the differential absorption of left- and right-handed circularly polarized light, it provides critical insights into molecular conformation. Since the secondary structure of proteins directly influences circular dichroism spectra, this method finds broad applications in monitoring conformational changes, studying stability, analyzin......
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• Circular Dichroism for Proteins
Circular dichroism for proteins is a spectroscopic technique widely used to analyze the secondary structures of proteins, their conformational changes, and interactions with ligands. This method leverages the optical phenomenon of circular dichroism, which arises from the differential absorption of left- and right-handed circularly polarized light by chiral molecules. By recording CD spectra across various wavelengths, researchers can deduce the secondary structure composition of proteins, including α......
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• Circular Dichroism CD Spectra
Circular dichroism CD spectra is an essential spectroscopic technique widely used to investigate molecular structures, leveraging the differential absorption of circularly polarized light to provide insights into molecular chirality and configuration. This technique plays a crucial role in studying biomacromolecules, particularly proteins and nucleic acids, under near-physiological and non-destructive conditions. Circular dichroism CD spectra is invaluable in protein research for determining secondary......
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CD spectra of protein is a pivotal spectroscopic technique for exploring the structural properties of proteins. By measuring the differential absorption of left- and right-handed circularly polarized light, CD spectra offer detailed insights into the secondary structures of proteins. These secondary structures, including α-helices, β-sheets, and random coils, play crucial roles in determining protein function. Analyzing CD spectra of protein enables researchers to unravel intricate details about p......
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• Circular Dichroism (CD) Spectroscopy
Circular dichroism (CD) spectroscopy is a fundamental spectroscopic tool widely employed for molecular structural analysis, especially the study of biomacromolecule conformations. The method utilizes the differential absorption of circularly polarized light to provide structural insights, making it particularly useful in characterizing the secondary structures of proteins and nucleic acids. Understanding such structural details is critical since the biological activity of these macromolecules depends ......
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• Advancing Biomolecular Studies with Circular Dichroism CD Spectroscopy
Circular dichroism CD spectroscopy is a pivotal technique in molecular structure analysis, particularly for exploring the secondary structures of biomacromolecules. This spectroscopic method leverages the differential absorption of circularly polarized light to derive detailed structural information. Its application is especially prominent in analyzing proteins and nucleic acids. By measuring the spectral characteristics in the far-UV and near-UV regions, CD spectroscopy reveals critical data on α-hel......
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