Resources

Proteomics Databases



Metabolomics Databases

• • Amino Acid Composition Analysis

  Amino acid composition analysis is a key method for quantifying and characterizing the types, proportions, and distribution of amino acids in protein or peptide samples. Amino acids are the basic units of proteins, determining their structure and function. The chemical properties of amino acids, such as polarity, acidity, hydrophobicity, and hydrophilicity, influence protein folding, stability, and molecular interactions. Amino acid composition analysis provides valuable insights into the roles of pro......

• • How Is Protein Identification Conducted Using Mass Spectrometry

  Protein identification conducted using mass spectrometry is an essential process in understanding the sequence, structure, and function of proteins. This multifaceted approach incorporates specific methodologies at each stage to ensure accurate and comprehensive protein characterization.   1. Protein Extraction The initial step involves extracting proteins from biological materials such as cells or tissues through centrifugation, lysis, and solubilization. Purification steps employ chromatographic tec......

• • Protein Measurement Using Mass Spectrometry

  Protein measurement using mass spectrometry is a fundamental technique in modern proteomics research, enabling detailed analysis of protein composition, structure, and post-translational modifications. This approach allows researchers to gain valuable insights into the proteome, providing critical information for understanding cellular processes and disease mechanisms.   Sample Preparation 1. Protein Extraction The first step in protein measurement using mass spectrometry is extracting proteins from b......

• • Peptide Purity Testing

  Peptide purity testing is a fundamental procedure in evaluating and verifying peptide quality, crucial for ensuring the accuracy and reliability of experimental results. In proteomics research, peptides often serve as intermediates, derived either from the enzymatic digestion of larger proteins or through synthetic peptide production. They are widely applied in various fields, including liquid chromatography-mass spectrometry (LC-MS) analysis, protein quantification, and structural elucidation. The pu......

• • Mass Spectrometry for Protein Identification

  Mass spectrometry for protein identification is a widely-used technique that enables the identification and quantification of proteins within a sample. Its applications span biological research, clinical diagnostics, and drug discovery. In this process, mass spectrometry for protein identification plays a crucial role in discovering novel proteins, exploring protein modifications, and analyzing protein interactions and functions.   The procedure for Mass Spectrometry for Protein Identification consist......

• • Mass Spectrometry Detection in Proteomics

  Mass spectrometry detection in proteomics is an advanced analytical technique widely used to analyze protein samples, offering both qualitative and quantitative information. This technology has become essential in proteomics, providing detailed insights into protein expression, modifications, and interactions.   The core principle of mass spectrometry detection in proteomics involves the use of a mass spectrometer, which measures the mass-to-charge ratio (m/z) of ions. This allows the instrument to de......

• • Mass Spectrometry Analysis Workflow

  The mass spectrometry analysis workflow is a comprehensive methodology for determining molecular mass, structural features, and composition, making it indispensable in fields like chemistry, biology, pharmacology, and environmental science. In proteomics, it serves as a cornerstone for protein identification and the analysis of protein interactions. This workflow encompasses six main stages:   Sample Preparation 1. Purification Isolating target molecules from complex biological or chemical matrices en......

• • What Aspects of Proteins Can be Measured Using Mass Spectrometry?

  Mass spectrometry (MS) is a versatile analytical technique widely used in proteomics to measure various aspects of proteins. It has revolutionized our ability to identify and quantify proteins, assess post-translational modifications (PTMs), and investigate complex protein interactions.   Protein Identification Mass spectrometry facilitates the identification of proteins by analyzing the mass-to-charge ratio (m/z) and fragmentation spectra of peptides or proteins, allowing precise identification of pr......

• • Mass Spectrometry in Protein Analysis

  Mass spectrometry in protein analysis has become indispensable for understanding complex cellular processes at the molecular level. Mass spectrometry is a pivotal technique in protein analysis, providing essential information on the mass, structure, composition, and quantification of proteins. Through mass spectrometry analysis, researchers can identify unknown proteins, characterize protein complexes, detect post-translational modifications, quantify protein levels, and investigate protein dynamics. ......

• • Proteomics Research Using Mass Spectrometry

  Proteomics research using mass spectrometry (MS) has become indispensable for identifying and quantifying cellular proteins, offering insights into their functions and interactions. As a cornerstone of biomedical innovation, mass spectrometry has propelled advancements in understanding disease mechanisms, biomarker discovery, and drug development.   Applications of Mass Spectrometry in Proteomics Proteomics research using mass spectrometry encompasses several critical applications:   1. Protein Identi......