Resources

Proteomics Databases



Metabolomics Databases

• • Protein Group Verification

  Protein validation aims to confirm the existence of proteins, identify their characteristics, and understand their roles and interactions in biological processes. This validation method is crucial for gaining a deeper understanding of the roles and functions of proteins in organisms and for advancing biomedical research and drug development.

• • Single-Cell Proteomics Research

  Single-cell proteomics is a field that studies the expression and regulation of proteins within individual cells. This level of resolution provides researchers with a deeper understanding of cellular heterogeneity, microenvironmental influences, and interactions between cells. It complements single-cell genomics and single-cell transcriptomics, together providing a more comprehensive view of cellular-level biological information.

• • SWATH Quantitative Proteomics

  "SWATH" stands for "Sequential Window Acquisition of all Theoretical Mass Spectra," which is a mass spectrometry technique commonly used for quantitative proteomics analysis. Today, I will introduce the basic principles and characteristics of SWATH quantitative proteomics.

• • Antibody Drug Mycoplasma Detection

  Antibody drugs are a type of biopharmaceutical used to treat various complex diseases, including autoimmune diseases, inflammatory diseases, and cancer. These drugs are produced through complex biotechnology techniques in cell culture systems, typically involving mammalian cell lines such as Chinese Hamster Ovary (CHO) cells.

• • Antibody Drug Excipient Detection

  As a class of therapeutic biological products, antibody drugs require precise biotechnology techniques and rely on various raw materials to support drug production and stability. These raw materials include but are not limited to amino acids, carbohydrates, protein stabilizers, buffers, surfactants, etc., which play an essential role in ensuring the efficiency of cell culture processes, the purity of antibody drugs, and the quality of the final formulation.

• • Antibody Drug Ultraviolet Spectrum Analysis

  Antibody drugs, as a breakthrough in biotechnology, are now widely used in the treatment of various diseases, including cancer, autoimmune diseases, and infectious diseases. These drugs are usually precisely designed protein molecules that can specifically bind to targets in the human body, such as specific molecules on pathogens or diseased cells, thereby guiding the attack of the immune system or directly blocking the pathological process.

• • Secretomics

  Secreted proteins refer to proteins that are synthesized by cells and secreted into the extracellular space. They play important roles in various biological processes, such as signal transduction, intercellular communication, immune response, and hormone secretion. These proteins are usually synthesized in the endoplasmic reticulum (ER) of cells and then transported to the extracellular space through a series of biosynthesis and transport processes.

• • Untargeted Proteomics Sequencing

  Untargeted Proteomics Sequencing aims to comprehensively analyze all proteins in a biological sample, rather than focusing on specific proteins. It helps study the complexity of the proteome and discover new protein biomarkers. Protein sequencing is the process of determining the amino acid sequence of a protein.

• • Proteomic Screening for Differential Proteins

  Proteomics is a method for studying the composition and function of all proteins expressed in an organism. Screening for differentially expressed proteins is one of the important tasks in proteomics research, as it helps researchers identify proteins that show changes in expression levels under different conditions or in different tissues, thus providing insights into biological processes and disease mechanisms within organisms.

• • How to Detect the Level of Histone Methylation?

  Histone methylation refers to the process of adding methyl groups to specific lysine (Lys) and arginine (Arg) residues on histone proteins. This is a common epigenetic modification that has significant effects on chromatin structure and gene expression regulation. Detecting the level of histone methylation is one of the fundamental techniques in the study of epigenetics. Here are some commonly used detection methods: