Sequencing Analysis

• • N-Glycosylation Site Profiling Service

  Protein N-glycosylation is a vital post-translational modification in life sciences, playing a significant role in both physiological and pathological processes. Precise analysis of N-glycosylation sites—including evaluating both the overall occupancy of these sites and the specific sugar structures at each site—is critical for understanding the biosynthesis and functionality of glycoproteins.

• • Protein Full Spectrum Analysis Service

  MtoZ Biolabs excels in delivering top-tier full-spectrum protein analysis services, aiding researchers in deciphering biological complexities. At its heart, the lab employs a combination of shotgun proteomics, high-performance liquid chromatography (HPLC), and mass spectrometry (MS) to identify and quantify proteins in intricate biological samples accurately.

• • Protein Primary Structure Analysis Service

  MtoZ Biolabs employs an LC-MS/MS analytical platform integrated with bioinformatics to offer protein primary structure analysis services. This platform enables the precise determination of amino acid sequences and modification sites, including critical post-translational modifications like phosphorylation, glycosylation, and ubiquitination, thereby accurately characterizing the primary structures of target proteins.

• • Peptidomic Analysis Service

  Peptidomics is a scientific discipline dedicated to studying peptides within organisms, focusing on their composition, structure, functions, and roles in biological processes. It primarily investigates peptides, molecules formed by short chains of amino acids linked by peptide bonds. These peptides can be naturally occurring or synthetically produced through biotechnological means. Peptides play pivotal roles in numerous biological processes, including serving as hormones and neurotransmitters, participatin

• • Proteomics Analysis Services, Biopharmaceutical Characterization Services, Bioinformatics Services

  MtoZ Biolabs specializes in elucidating the intricate nature of proteins, peptides, antibodies, vaccines, and biopharmaceuticals at the molecular level. We maintain close collaborations with numerous pioneering institutions in the fields of proteomics, biopharmaceuticals, and bioinformatics sequencing technologies, jointly developing a high-quality and innovative service portfolio to bolster proteomics research and biopharmaceutical development endeavors.

• • Proteomics Based on MS Analysis Service

  Proteomics is the study of the complete set of proteins expressed within cells, tissues, or individuals. With the advent of mass spectrometry (MS)-based protein analysis technologies, large-scale protein profiling has become widely accessible. Proteomics encompasses diverse processes such as protein expression profiling, protein modifications, protein-protein interactions, protein structures, and protein functions. The outcomes derived from these endeavors facilitate the deciphering of disease processes, of

• • Protein Mass Spectrometry Identification Service

  Mass spectrometry (MS), a cornerstone tool in modern proteomics research, boasts unparalleled high-throughput analytical capabilities. In the MS-guided protein identification workflow, complex protein samples are first digested into peptides, which are then subjected to a series of intricate manipulations, including efficient separation, precise fragmentation, and ionization, to render them detectable by the mass spectrometer. With its exceptional sensitivity, the mass spectrometer captures and records the

• • Protein Identification Analysis Service

  The identification and quantification of proteins expressed by an entire organism under certain conditions constitute the primary focus of high-throughput proteomics. High-throughput (HTP) proteomics aims to investigate the dynamically changing proteins expressed by an entire organism, specific tissues, or cellular compartments under defined conditions. Consequently, the two primary objectives of proteomics research are to identify proteins from complex mixtures extracted from cells and to quantitatively de

• • O-Glycan Analysis Service

  O-glycosylation, a complex and diverse modification within the vast realm of protein modifications, substantially enriches protein functionality. Unlike N-glycosylation, O-glycosylation poses significant challenges due to the complex nature of its glycan structures and the difficulty in accurate characterization. This modification predominantly involves attaching O-linked glycan chains to Serine, Threonine, or occasionally Tyrosine residues of proteins, with O-linked N-acetylgalactosamine (O-GalNAc) being t

• • N-Glycan Profiling Service

  Glycosylation is a pivotal post-translational modification that attaches monosaccharides or oligosaccharides to proteins, influencing their structure and functionality. This modification enhances molecular diversity but introduces challenges in analysis due to the complexity and variability of glycan structures. N-glycosylation, the predominant form of glycosylation, involves linking glycan groups to the asparagine side chain of proteins. It is essential for regulating biological processes such as protein-