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    Sphingolipid Analysis Service

      Sphingolipids are a complex class of lipids that play crucial roles in cellular structure and function. They are essential components of cell membranes and are involved in various biological processes, including cell signaling, apoptosis, and differentiation. Sphingolipids consist of a sphingoid base backbone, commonly sphingosine, linked to a fatty acid, forming ceramide, which can be further modified with different head groups to produce diverse sphingolipid species such as sphingomyelins, glycosphingolipids, and gangliosides.

       

      Research into sphingolipids is of significant importance due to their involvement in numerous physiological and pathological processes. Dysregulation of sphingolipid metabolism is associated with various diseases, including neurodegenerative disorders, cancer, metabolic syndromes, and inflammatory conditions. Understanding the complex sphingolipid metabolic pathways and their regulatory mechanisms can provide insights into disease mechanisms and identify potential therapeutic targets.

       

      At MtoZ Biolabs, our sphingolipid analysis service utilizes liquid chromatography-mass spectrometry (LC-MS/MS), a powerful tool for the identification and quantification of sphingolipids. The method involves separation of sphingolipids by liquid chromatography, followed by their ionization and detection using mass spectrometry. This approach enables high-throughput analysis of sphingolipids, with high sensitivity and specificity.

       

      Analysis Workflow

       

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      Service Advantages

      • Comprehensive Coverage: Identification and quantification of a wide range of sphingolipid species are provided.
      • High Sensitivity and Accuracy: The advanced LC-MS/MS platform ensures high sensitivity and accuracy in analyses.
      • Expertise: A team of experienced scientists and technicians, proficient in sphingolipid analysis, ensures the delivery of exceptional results.
      • Customizable: Personalized service to meet various research needs.

       

      Applications

      Our sphingolipid analysis service is applicable in a variety of research areas, including:

      • Lipidomics research
      • Drug development and pharmacokinetics
      • Biomarker discovery
      • Disease pathogenesis studies
      • Nutritional and environmental studies

       

      Sample Submission Requirements

      • Type of samples: Plasma, serum, cell, tissue, etc.
      • Quantity: At least 200 μl liquid, 1 x 10⁷ cells, or 200 mg tissue.
      • Storage and Shipping: Samples should be stored at -80℃ and shipped with dry ice.
      • Note: Avoid repeated cycles of freezing and thawing

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Sphingolipid Analysis

      4. Raw Data

      5. Custom Analysis Report

       

      Contact MtoZ Biolabs for more information about our sphingolipid analysis service, pricing and turnaround time. We are committed to providing the best service to accelerate your research.

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