Succinate and Succinic Acid Analysis Service
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
Succinate and succinic acid are key intermediates in the tricarboxylic acid (TCA) cycle, widely present in plants, animals, and microorganisms. Succinic acid is a crucial organic acid that plays a vital role in energy metabolism and cellular respiration. It is produced from succinate via succinate dehydrogenase (SDH), converting it to fumarate while transferring electrons to the electron transport chain. In living organisms, succinic acid exists in the form of the succinate anion, serving multiple biological functions as both a metabolic intermediate and a signaling molecule reflecting the metabolic state of the cell. Additionally, succinic acid participates in various metabolic pathways, including the synthesis and degradation of amino acids and fatty acids.
Succinate and succinic acid are significant in both biological systems and industrial applications. They are used as food additives to enhance flavor and regulate acidity. In the pharmaceutical field, succinic acid derivatives are developed for treating metabolic diseases. In the chemical industry, succinic acid is used in producing plastics, resins, and dyes.
Given their multiple functions in biological systems and wide industrial applications, accurately measuring the content of succinate and succinic acid in biological samples is crucial for clinical diagnosis, metabolic research, and industrial applications.
Figure 1. Molecular Structure of Succinic Acid
MtoZ Biolabs offers Succinate and Succinic Acid Analysis Service using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). This advanced method combines the separation capabilities of UPLC with the detection power of MS, ensuring high sensitivity and specificity in succinate and succinic acid detection.
Analysis Workflow
Service Advantages
Sample Submission Requirements
Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.
Applications
1. Cellular Metabolism Research: Quantifying succinate and succinic acid levels provides insights into the function of the TCA cycle, revealing cellular metabolic states and energy production efficiency.
2. Disease Biomarker Identification: Changes in succinate and succinic acid levels can serve as biomarkers for various diseases and conditions, linked to mitochondrial dysfunction, cancer, cardiovascular diseases, and neurodegenerative disorders.
3. Drug Impact Assessment: Evaluating the effect of potential drugs on succinate metabolism helps determine their impact on cellular energy production and mitochondrial function, aiding in the development of new therapeutics.
4. Food and Nutrition Research: Analyzing succinate and succinic acid content in food and nutritional supplements optimizes dietary intake strategies and health assessments.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Succinate and Succinic Acid
4. Raw Data
5. Custom Analysis Report
Our Succinate and Succinic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.
How to order?
