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    Sulfur Metabolism Service

      Sulfur is an essential element for all living organisms, playing a pivotal role in various cellular functions. It is a key component of amino acids such as cysteine and methionine, vitamins like biotin and thiamine, and numerous coenzymes and metabolic intermediates. 

       

      The sulfur metabolic pathway begins with the uptake of sulfate from the environment, followed by its reduction to sulfide through the action of enzymes such as ATP sulfurylase, APS reductase, and sulfite reductase. Sulfide is then incorporated into organic molecules through the action of cysteine synthase, forming cysteine, which serves as a building block for proteins and other sulfur-containing biomolecules. Cysteine can be further metabolized to produce glutathione, a critical antioxidant, and other important sulfur metabolites.

       

      Abnormalities in sulfur metabolism are linked to a range of health issues, including metabolic disorders, oxidative stress-related diseases, and disruptions in cellular signaling pathways. For instance, defects in cysteine metabolism can lead to disorders such as cystinosis and homocystinuria. Furthermore, sulfur metabolites like hydrogen sulfide (H2S) have been recognized for their signaling functions and potential therapeutic applications.

       

      At MtoZ Biolabs, we provide a comprehensive Sulfur Metabolism Service to analyze sulfur-containing metabolites and pathways, supporting your research in the field of sulfur biology and metabolism. Our Sulfur Metabolism Service is based on advanced mass spectrometry (MS) technology, coupled with cutting-edge high-performance liquid chromatography (HPLC). The sulfur-containing metabolites in the samples are separated by HPLC and then detected by MS. Afterward, our bioinformatics team processes and analyzes the data to identify and quantify sulfur-containing metabolites, offering insights into the sulfur metabolism in the tested samples.

       

      Analysis Workflow

       

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      Service Advantages

      • Technical Expertise: A team with extensive experience in mass spectrometry and sulfur metabolism analysis ensures the delivery of exceptional results.
      • Advanced Technology: State-of-the-art HPLC-MS technology provides high sensitivity and accuracy.
      • Comprehensive Analysis: Provides a complete picture of sulfur metabolism, including both identification and quantification of sulfur-containing metabolites.
      • Customizable: Personalized service to meet various research needs.

       

      Applications

      Our Sulfur Metabolism Service can be applied in numerous research areas, including but not limited to:

      • Disease Research: Understanding of sulfur metabolism in various diseases.
      • Drug Discovery: Identification of potential therapeutic targets related to sulfur metabolism.
      • Nutritional Studies: Investigation of the role of sulfur in diet and nutrition.

       

      Sample Submission Requirements

      • Type of samples: Plasma, serum, cell, tissue, etc.
      • Quantity: At least 500 μl liquid, 1 x 10⁷ cells, or 500 mg tissue.
      • Storage and Shipping: Samples should be stored at -80℃ and shipped with dry ice.
      • Note: Avoid repeated cycles of freezing and thawing

      For more details, please feel free to get in touch with our customer service team.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant High-Performance Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Sulfur Metabolism Analysis

      4. Raw Data

      5. Custom Analysis Report

       

      At MtoZ Biolabs, we are committed to providing high-quality, reliable data to support your research. Contact us today to learn more about our Sulfur Metabolism Service.

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