Urea Analysis Service

Urea is the primary end product of protein metabolism, essential for nitrogen balance and waste excretion in the body. It is synthesized in the liver through the urea cycle and excreted by the kidneys. Fluctuations in urea levels can indicate the functional status of the liver and kidneys, serving as a critical biomarker for diagnosing and monitoring kidney disease, liver disease, and metabolic disorders. Moreover, urea is widely used in agriculture, food, and chemical industries. Therefore, accurate measurement of urea content is crucial for medical research, clinical diagnostics, and industrial applications.

 

 

Figure 1. Molecular Structure of Urea

 

MtoZ Biolabs offers Urea Analysis Service using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of urea in complex biological matrices.

 

Analysis Workflow

 



 

Service Advantages

 



 

Sample Submission Requirements

Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

 

Sample Volume

At least 200 μL of liquid sample or 200 mg of tissue sample.

 

Sample Preservation

Store and transport samples at -80 °C.

 

Applications

Clinical Diagnosis: Measure urea levels to assist in diagnosing and monitoring kidney diseases, liver diseases, and metabolic disorders.

 

Metabolic Research: Study the metabolic pathways of urea in humans and animals to understand its roles under different physiological conditions.

 

Drug Metabolism Research: Evaluate the role of urea in drug metabolism, studying its importance in drug development and drug interactions.

 

Food and Agriculture Research: Analyze urea content in food and agricultural products to ensure product quality and safety.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Urea

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into urea's extensive physiological roles through top-tier analytical techniques and expert services.