Various Types of N-glycan Analysis Service
- Advanced MS technology for accurate identification and quantification of N-glycans
- Comprehensive service from sample preparation to data interpretation
- High reproducibility and reliability
- Customizable service to meet specific research needs
- Competitive pricing and quick turnaround time
- Characterization of glycosylation patterns in biomarker discovery
- Investigation of glycan changes in disease progression
- Analysis of glycan structures in therapeutic protein development
- Evaluation of glycosylation in cell line engineering
- We accept various types of samples including plasma, serum, tissue, cells, and urine.
- Please ensure your submitted sample surpasses 0.5 g or 0.5 mL.
- Samples should be stored in a -80℃ environment and transported on dry ice.
N-glycosylation is one of the most important and complex post-translational modifications (PTMs) that plays crucial roles in various biological processes. N-glycans are complex carbohydrate structures covalently attached to proteins through N-linked glycosidic bonds, typically occurring at asparagine residues within the consensus sequon Asn-X-Ser/Thr. These glycans play crucial roles in protein folding, stability, and function, influencing cellular processes such as signal transduction, immune response, and cell-cell recognition. The biosynthesis of N-glycans begins in the endoplasmic reticulum and continues in the Golgi apparatus, involving a series of enzymatic modifications that generate heterogeneous glycan structures. Research into N-glycans has revealed their significant impact on glycoprotein activity and interactions, with implications for various diseases, including cancer and congenital disorders. Advances in glycomics and glycoproteomics have facilitated a deeper understanding of N-glycan functions, highlighting their potential as biomarkers and therapeutic targets in precision medicine.
Services at MtoZ Biolabs
At MtoZ Biolabs, we have developed a comprehensive N-glycan analysis service to help you unravel the intricacies of your sample's glycosylation patterns. We utilize innovative techniques like Liquid Chromatography-Mass Spectrometry (LC-MS) and Matrix-Assisted Laser Desorption/Ionization (MALDI-TOF/TOF) MS. These techniques enable the separation, identification, and quantification of a wide variety of N-glycans in complex biological samples. Furthermore, we offer label-free and label-based quantitative glycomics analysis depending on your specific requirements and research goals.
Analysis Workflow
Service Advantages
Applications
Our N-glycan analysis service can be applied in various research scenarios, including but not limited to:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Various Types of N-glycan Analysis
4. Mass Spectrometry Images
5. Raw Data
For any further questions on our N-glycan analysis service, please do not hesitate to reach out to our customer service team at MtoZ Biolabs.
How to order?
